ACLP/AEBP1 Inhibitors
ACLP/AEBP1 inhibitors belong to a distinctive chemical class characterized by their ability to modulate the activity of ACLP (Adipocyte enhancer-binding protein 1) or AEBP1 (Adipocyte enhancer-binding protein 1). ACLP/AEBP1, a multifaceted protein, plays a pivotal role in various cellular processes, particularly in adipocytes. These inhibitors are designed to specifically target the regulatory functions of ACLP/AEBP1, influencing downstream signaling pathways and cellular responses. The chemical entities within this class are meticulously crafted to interfere with the interaction between ACLP/AEBP1 and its binding partners, thereby exerting a regulatory influence on cellular processes governed by this protein.ACLP/AEBP1 inhibitors often exhibit a diverse array of chemical scaffolds, reflecting the intricate nature of the interactions they disrupt.
Researchers leverage a comprehensive understanding of the three-dimensional structure of ACLP/AEBP1 and its binding sites to design small molecules capable of fitting into these specific regions, either obstructing interactions or modulating the conformational dynamics of the protein. The intricate design of these inhibitors showcases a sophisticated approach to manipulating cellular pathways associated with ACLP/AEBP1, shedding light on the intricacies of adipocyte function and broader physiological implications.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is a potent inhibitor of mTOR signaling, which is involved in cellular processes that AEBP1 regulates, such as cell growth and proliferation. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid that inhibits PI3K/Akt signaling, a pathway that can influence AEBP1 activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a specific inhibitor of PI3K, which can influence AEBP1 activity via the PI3K/Akt pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a selective inhibitor of MEK, which can indirectly affect AEBP1 activity through the MAPK/ERK pathway. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a polyphenol that modulates sirtuin activity, which can influence AEBP1 activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a selective inhibitor of JNK, which can indirectly affect AEBP1 activity through the MAPK pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective inhibitor of p38 MAPK, which can influence AEBP1 activity through the MAPK pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent and selective inhibitor of PI3K, which can influence AEBP1 activity via the PI3K/Akt pathway. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632 is a selective inhibitor of ROCK, a kinase that can influence AEBP1 activity through the Rho/ROCK pathway. | ||||||