GSK-3 beta Inhibitors

Santa Cruz Biotechnology now offers a broad range of GSK-3 beta Inhibitors. Glycogen synthase kinase 3, or GSK-3, is a serine/threonine, proline-directed kinase involved in a diverse array of signaling pathways, including glycogen synthesis and cellular adhesion. GSK-3 phosphorylates Tau proteins and it is thought that miscues in GSK-3 signaling may contribute to the onset of Alzheimer's disease. GSK-3 beta Inhibitors offered by Santa Cruz inhibit GSK-3 beta and, in some cases, other cell signaling and Alzheimer's disease related proteins. View detailed GSK-3 beta Inhibitor specifications, including GSK-3 beta Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/ApplicationCASCatalog #QUANTITYPriceCitationsRATING
Valproic acid sodium salt
An HDAC inhibitor with anticancer, anti-inflammatory and neuroprotective effects
1069-66-5sc-202378
5 g
$31.00
6
(1)
Staurosporine
An antifungal inhibitor of many different enzymes
62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$75.00
$140.00
$380.00
51
(4)
KT 5720
A potent, specific and cell-permeable inhibitor of PKA
108068-98-0sc-3538
sc-3538A
50 µg
100 µg
$85.00
$131.00
31
(2)
GSK-3 Inhibitor IX
A cell-permeable, potent, selective, reversible GSK-3α/β inhibitor
667463-62-9sc-202634
sc-202634A
sc-202634B
1 mg
10 mg
50 mg
$56.00
$180.00
$850.00
6
(1)
Ro 31-8220
A cell-permeable PKC inhibitor that has been shown to be selective for PKC over CaM kinase II and PKA
138489-18-6sc-200619
1 mg
$81.00
9
(1)
SB-216763
A potent, selective and ATP-competitive inhibitor of GSK-3α and GSK-3β
280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$64.00
$189.00
15
(1)
CID 755673
A selective PKC, PKD, Plk, and HSP 27 inhibitor
521937-07-5sc-205246
10 mg
$199.00
0
(1)
Kenpaullone
A Cdk and GKS-3 inhibitor
142273-20-9sc-200643
sc-200643A
sc-200643B
sc-200643C
1 mg
5 mg
10 mg
25 mg
$59.00
$147.00
$222.00
$485.00
1
(1)
Lithium Chloride
For assays to study cell-fate, neurobiology and antiviral properties; noted to inhibit GSK-3β
7447-41-8sc-203110
sc-203110A
sc-203110B
sc-203110C
sc-203110D
sc-203110E
50 g
250 g
1 kg
2.5 kg
5 kg
10 kg
$21.00
$41.00
$160.00
$330.00
$592.00
$1,130.00
2
(2)
GSK-3beta Inhibitor XII, TWS119
A cell-permeable agent shown to act as a potent inhibitor of GSK-3β
601514-19-6sc-221694
sc-221694A
1 mg
5 mg
$55.00
$150.00
4
(1)
GSK-3 Inhibitor XVI
A compound that acts as potent, ATP-competitive & highly selective GSK-3 inhibitor
252917-06-9sc-221691
sc-221691A
5 mg
25 mg
$285.00
$890.00
2
(1)
10Z-Hymenialdisine
An ATP competitive, CK1 and GSK-3β inhibitor
82005-12-7sc-360987
500 µg
$206.00
0
(1)
Indirubin
An inhibitor of GSK-3β and cyclin-dependent kinases
479-41-4sc-201531
sc-201531A
5 mg
25 mg
$105.00
$269.00
1
(1)
CHIR-98014
A selective and ATP-competitive inhibitor of GSK-3β
252935-94-7sc-364465
sc-364465A
5 mg
25 mg
$300.00
$1,035.00
1
(0)
GSK-3beta Inhibitor VI
A cell-permeable, irreversible, and non-ATP competitive inhibitor of GSK-3β
62673-69-2sc-221693
5 mg
$145.00
0
(0)
Manzamine A
A β-Carboline alkaloid with anti-inflammatory
104196-68-1sc-202220
1 mg
$224.00
0
(1)
Indirubin-3′-monoxime
A potent inhibitor of GSK-3β, Cdk1, and Cdk5
160807-49-8sc-202660
sc-202660A
sc-202660B
1 mg
5 mg
50 mg
$75.00
$309.00
$645.00
0
(1)
GSK-3 Inhibitor X
A selective GSK-3α/β inhibitor
740841-15-0sc-221689
5 mg
$130.00
3
(1)
GSK-3 Inhibitor XV
A highly bioreactive inhibitor to GSK-3α, GSK-3β. and PIM-1 kinase
sc-221690
1 mg
$539.00
0
(1)
SB-415286
An ATP-competitive inhibitor of GSK3α and GSK-3β
264218-23-7sc-204901
sc-204901A
1 mg
5 mg
$62.00
$140.00
3
(1)
1-Azakenpaullone
A Kenpaullone analog and an inhibitor of GSK-3
676596-65-9sc-358615
1 mg
$96.00
0
(0)
TWS 119 ditrifluoroacetate
A cell-permeable GSK-3β inhibitor
601514-19-6 (non-salt)sc-358727
10 mg
$195.00
0
(0)
5-Iodo-indirubin-3prime-monoxime
An inhibitor of GSK-3β, CDK1/cyclin B and CDK5/p25
sc-221030
1 mg
$78.00
0
(0)
GSK-3β Inhibitor I
A thiadiazolidinone analog that acts as a highly selective, non-ATP competitive inhibitor of GSK-3β
327036-89-5sc-221692
sc-221692A
5 mg
25 mg
$179.00
$282.00
1
(0)
5-Iodo-Indirubin-3prime-monoxime
An inhibitor of GSK-3β, CDK-1, and CDK-5
sc-221754
1 mg
$104.00
0
(0)
Indirubin-5-sulfonic acid sodium salt
A CDK and GSK-3β inhibitor
sc-221755
sc-221755A
1 mg
5 mg
$57.00
$324.00
0
(0)
GSK-3beta Inhibitor VII
A cell-permeable, and non-ATP competitive inhibitor of GSK-3β
99-73-0sc-202635
5 mg
$129.00
0
(0)
Cdk1/5 Inhibitor Inhibitor
A 3-amino substituted pyrazoloquinoxaline compound and selective inhibitor of Cdk1/Cdk5
40254-90-8sc-202094
sc-202094A
sc-202094B
1 mg
5 mg
10 mg
$60.00
$200.00
$360.00
2
(1)
Hymenidin
An antagonist of serotonergic receptors and inhibitor of CDK5/p25 and GSK-3β
107019-95-4sc-202177
1 mg
$258.00
0
(0)
Bisindolylmaleimide X hydrochloride
A selective inhibitor of PKC, also inhibits Cdk2 and GSK-3β
131848-97-0sc-221368
sc-221368A
1 mg
5 mg
$49.00
$163.00
0
(0)
3F8
A selective and potent GSK-3β inhibitor
159109-11-2sc-361080
sc-361080A
10 mg
50 mg
$159.00
$670.00
0
(0)
Isogranulatimide
Cell-permeable alkaloid that acts as a potent and ATP-competitive inhibitor of Chk1
244148-46-7sc-202667
1 mg
$700.00
0
(0)
CR8, (R)-Isomer
A cell-permeable, ATP-binding pocket-targeting CDK/CK1 dual-specific inhibitor
294646-77-8sc-311306
5 mg
$174.00
0
(0)
L-779,450
A potent, ATP-competitive Raf kinase inhibitor
303727-31-3sc-204046
sc-204046A
10 mg
50 mg
$131.00
$739.00
0
(2)
Indirubin-3prime-monoxime-5-sulphonic Acid
An inhibitor of GSK-3β, Cdk1 and Cdk5.
331467-05-1sc-221753
1 mg
$179.00
0
(0)
GSK-3 Inhibitor II
A potent GSK-3β inhibitor
478482-75-6sc-24020
sc-24020A
5 mg
25 mg
$80.00
$290.00
9
(1)
GSK-3beta Inhibitor VIII
A potent, selective inhibitor of GSK-3β
487021-52-3sc-202636
sc-202636A
5 mg
10 mg
$128.00
$144.00
3
(1)
Aloisine A
An inhibitor of CDK1, CDK2, CDK5, GSK-3 alpha, and JNK
496864-16-5sc-202451
1 mg
$45.00
0
(0)
GSK-3beta Inhibitor XI
A potent and specific ATP-competitive inhibitor of GSK-3Β
626604-39-5sc-204770
1 mg
$224.00
1
(1)
GSK-3 Inhibitor IX, Control, MeBIO
A cell-permeable N-methylated kinase inactive analog of GSK-3 Inhibitor IX
710323-61-8sc-221688
1 mg
$135.00
0
(1)
Alsterpaullone, 2-Cyanoethyl
A selective inhibitor of Cdk1/cyclin B and GSK-3β
852529-97-0sc-203815
1 mg
$320.00
0
(0)
TCS 2002
A cell-permeable inhibitor of GSK-3β
1005201-24-0sc-359020
sc-359020A
10 mg
50 mg
$175.00
$739.00
0
(0)
TCS 21311
A potent inhibitor of JAK3
1260181-14-3sc-362804
sc-362804A
10 mg
50 mg
$229.00
$970.00
0
(0)
A 1070722
An inhibitor of GSK-3α and GSK-3β with a Ki = 0.6 nM respectively
1384424-80-9sc-364392
sc-364392A
10 mg
50 mg
$131.00
$709.00
0
(0)
Ro-31-8220 in solution
A serotonin 1A-receptor agonist used experimentally to test the effects of serotonin
138489-18-6sc-358721
1 mg
$99.00
1
(0)
Enzastaurin
A potent inhibitor of PKCβ, PKCα, PKCγ and PKCε
170364-57-5sc-364488
sc-364488A
10 mg
50 mg
$135.00
$555.00
0
(1)
MeBIO
A control analog of BIO which displays minimal activity against CDK1/Cyclin B & GSK-3 α/β
667463-95-8sc-357370
10 mg
$160.00
1
(1)
Cdk2/9 Inhibitor
A cell-permeable aminopyrimidinyl compound
507487-89-0sc-221411
5 mg
$398.00
1
(0)
Cdk1/2 Inhibitor III
A cell-permeable triazolo-diamine compound and ATP inhibitor
443798-55-8sc-202530
1 mg
$198.00
0
(1)
PHA 767491 hydrochloride
A potent, ATP-competitive dual cdc7/cdk9 inhibitor
942425-68-5sc-204187
sc-204187A
10 mg
50 mg
$129.00
$548.00
3
(2)
AR-AO 14418-d3
A labeled Glycogen Synthase Kinase 3β (GSK-3β) inhibitor
sc-217659
5 mg
$1,353.00
0
(0)
Indole-3-acetamide
A GSK-3β, VEGF, and JAK3 inhibitor
879-37-8sc-255213
sc-255213A
1 g
5 g
$44.00
$198.00
0
(0)
Hymenialdisine Analogue 1
A potent inhibitor of a variety of kinases
693222-51-4sc-280808
1 mg
$350.00
0
(0)
6-N-[2-[[4-(2,4-dichlorophenyl)-5-(1H-imidazol-2-yl)pyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine
An inhibitor of glycogen synthase kinase-3 (GSK-3)
556813-39-9sc-207421
5 mg
$237.00
0
(1)

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