Molecular structure of 3F8, CAS Number: 159109-11-2
3F8 (CAS 159109-11-2)
See product citations (2)
Application:
3F8 is a selective and potent GSK-3β inhibitor
CAS Number:
159109-11-2
Purity:
>99%
Molecular Weight:
286.28
Molecular Formula:
C15H14N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
This compound has been shown to act as a selective and potent GSK-3β inhibitor.
3F8 (CAS 159109-11-2) References
- Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling. | Zhong, H., et al. 2009. Mol Biosyst. 5: 1356-60. PMID: 19823752
- Benzo[e]isoindole-1,3-diones as potential inhibitors of glycogen synthase kinase-3 (GSK-3). Synthesis, kinase inhibitory activity, zebrafish phenotype, and modeling of binding mode. | Zou, H., et al. 2010. J Med Chem. 53: 994-1003. PMID: 20030405
- Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells via a GSK-3β-Dependent Mechanism. | Shyu, HY., et al. 2016. J Cell Biochem. 117: 881-93. PMID: 26365534
- Anaphylatoxin C5a receptor signaling induces mitochondrial fusion and sensitizes retinal pigment epithelial cells to oxidative stress. | Ishii, M. and Rohrer, B. 2023. Biochim Biophys Acta Gen Subj. 1867: 130374. PMID: 37187450
Inhibitor of:
GSK-3 beta.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3F8, 10 mg | sc-361080 | 10 mg | $179.00 | |||
| US: Only available in the US | ||||||
3F8, 50 mg | sc-361080A | 50 mg | $756.00 | |||
| US: Only available in the US | ||||||