6720457D02Rik Inhibitors
Chemical inhibitors of the protein 6720457D02Rik can play a significant role in modulating its activity within cellular processes. Staurosporine, as a potent kinase inhibitor, can prevent the phosphorylation of 6720457D02Rik, leading to a decrease in its activity if phosphorylation is a requirement for its function. Similarly, Bisindolylmaleimide I can specifically target Protein Kinase C, which can be essential for the activation of 6720457D02Rik. This targeted inhibition can suppress the phosphorylation process, thereby reducing the activity of the protein. The chemical LY294002 can inhibit phosphoinositide 3-kinases (PI3K), which, if acting as upstream regulators, can diminish the activation of downstream pathways that include 6720457D02Rik. Wortmannin, another PI3K inhibitor, can also reduce the activity of this protein by affecting the Akt signaling pathway.
Moreover, PD98059 and U0126, both of which selectively inhibit MEK1/2 within the MAPK/ERK pathway, can prevent the activation of 6720457D02Rik by inhibiting the necessary upstream signals for its activity. SB203580, an inhibitor of p38 MAP kinase, and SP600125, a JNK inhibitor, can each target different pathways that regulate stress responses and other cellular processes, which can result in a reduction of 6720457D02Rik activity. Rapamycin, which inhibits the mTOR pathway, can affect the regulation of the protein by interfering with a pathway that can be involved in 6720457D02Rik's regulation. Lastly, PP2, Dasatinib, and Imatinib, which are inhibitors of Src family kinases and broad-spectrum tyrosine kinases respectively, can inhibit various signaling processes that may control the phosphorylation state and thus the activity of 6720457D02Rik. Each of these chemical inhibitors can interact with specific kinases or pathways, leading to a decrease in the protein's activity by preventing its phosphorylation or activation through different mechanisms within the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a kinase inhibitor that can inhibit the phosphorylation of 6720457D02Rik, assuming the protein's function is phosphorylation-dependent. This inhibition of kinase activity would lead to a reduction in 6720457D02Rik's activity by preventing its phosphorylation. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $105.00 $242.00 | 36 | |
Bisindolylmaleimide I specifically inhibits Protein Kinase C, which may be crucial for the activation of 6720457D02Rik. By inhibiting PKC, this chemical would hinder the phosphorylation and thus the activity of 6720457D02Rik. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits phosphoinositide 3-kinases (PI3K), which could be upstream regulators of 6720457D02Rik. By blocking PI3K, LY294002 could suppress the activation of downstream pathways essential for 6720457D02Rik function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is another PI3K inhibitor that would lead to diminished Akt signaling, potentially reducing the activity of 6720457D02Rik if it operates downstream of this pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 selectively inhibits MEK1/2, which is part of the MAPK/ERK pathway. Inhibition of this pathway would inhibit the activation of 6720457D02Rik if it is downstream of ERK. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 also inhibits MEK1/2, potentially reducing the activity of 6720457D02Rik by preventing the activation of ERK, which may be necessary for the proper functioning of 6720457D02Rik. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAP kinase, part of a stress-activated pathway that may regulate 6720457D02Rik. By disrupting p38 MAPK, SB203580 can reduce the activity of 6720457D02Rik. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), which might be involved in regulating 6720457D02Rik. Inhibiting JNK with SP600125 could then lead to a reduction in 6720457D02Rik's activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin inhibits the mTOR pathway, which may be involved in the regulation of cellular processes that include 6720457D02Rik. By inhibiting mTOR, Rapamycin would reduce the activity of 6720457D02Rik. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2 is an inhibitor of Src family kinases, which are related to various signaling processes that may involve 6720457D02Rik. By inhibiting Src kinases, PP2 would indirectly inhibit the activity of 6720457D02Rik. | ||||||