4930430E16Rik Inhibitors
Chemical inhibitors of 4930430E16Rik target various signaling pathways and molecular functions to exert their inhibitory effects on the protein. Wortmannin and LY294002 are phosphoinositide 3-kinases (PI3K) inhibitors that can disrupt the PI3K signaling cascade, possibly leading to the inhibition of 4930430E16Rik if it is regulated by PI3K-dependent phosphorylation. Additionally, Rapamycin, by targeting the mammalian target of rapamycin (mTOR), can inhibit 4930430E16Rik if there is a dependency on mTOR signaling for its function. Furthermore, PD98059 and U0126, which selectively inhibit mitogen-activated protein kinase kinase (MEK), can impede the MEK/ERK pathway and consequently inhibit 4930430E16Rik if its activity is regulated through this particular pathway.
In addition to these inhibitors, SP600125 operates by blocking c-Jun N-terminal kinase (JNK), which may inhibit 4930430E16Rik if it relies on JNK signaling. SB203580 targets p38 MAP kinase and can inhibit 4930430E16Rik by interfering with the p38 MAPK pathway. Additionally, WZ4003, which inhibits NUAK family SNF1-like kinase 1 (NUAK1), and PF-4708671, a selective inhibitor of p70 ribosomal S6 kinase (S6K1), can both obstruct the respective signaling pathways and potentially inhibit 4930430E16Rik if it is involved in those pathways. LDC000067, which selectively inhibits CDK9, could lead to the inhibition of 4930430E16Rik through the disruption of CDK9-dependent processes. Lastly, Chloroquine and Bafilomycin A1, which affect autophagy by preventing lysosomal acidification and inhibiting vacuolar-type H+-ATPase respectively, can inhibit 4930430E16Rik if its function is reliant on autophagic pathways or the proton gradient across lysosomal membranes.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin inhibits phosphoinositide 3-kinases (PI3K), which are involved in various cellular processes. Inhibition of PI3K can lead to the functional inhibition of 4930430E16Rik by disrupting signaling pathways it might be involved in, particularly if 4930430E16Rik's activity is regulated by PI3K-dependent phosphorylation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is another PI3K inhibitor that can disrupt downstream signaling pathways. The functional activity of 4930430E16Rik can be inhibited by LY294002 if the protein operates within the PI3K signaling axis, as the disruption of PI3K activity would impair 4930430E16Rik's function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits the mammalian target of rapamycin (mTOR), a key regulator of cell growth and proliferation. By inhibiting mTOR, Rapamycin can lead to the functional inhibition of 4930430E16Rik if the protein's function is linked to mTOR signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 selectively inhibits mitogen-activated protein kinase kinase (MEK), which is upstream of extracellular signal-regulated kinases (ERK). This inhibition can lead to functional inhibition of 4930430E16Rik if the protein's activity is regulated via the MEK/ERK pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a selective inhibitor of both MEK1 and MEK2, which may inhibit 4930430E16Rik by disrupting MEK/ERK signaling if the protein's function is regulated through this pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), which can inhibit the functional activity of 4930430E16Rik by interfering with JNK signaling pathways, assuming 4930430E16Rik relies on JNK for its function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective inhibitor of p38 MAP kinase, which can functionally inhibit 4930430E16Rik if it is involved in cellular responses regulated by p38 MAPK signaling. | ||||||
WZ4003 | 1214265-58-3 | sc-473979 | 5 mg | $300.00 | ||
WZ4003 inhibits NUAK family SNF1-like kinase 1 (NUAK1), which could functionally inhibit 4930430E16Rik if the protein's function is dependent on NUAK1-mediated signaling. | ||||||
PF 4708671 | 1255517-76-0 | sc-361288 sc-361288A | 10 mg 50 mg | $175.00 $700.00 | 9 | |
PF-4708671 is a selective inhibitor of p70 ribosomal S6 kinase (S6K1), which can lead to the functional inhibition of 4930430E16Rik if it plays a role in signaling pathways involving S6K1. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
Chloroquine inhibits autophagy by preventing lysosomal acidification and can functionally inhibit 4930430E16Rik if the protein requires autophagic degradation pathways for its regulation. | ||||||