4921528O07Rik Inhibitors
The class of MROH9 Inhibitors would include chemicals that can indirectly influence the activity of MROH9 by modulating metabolic pathways and cellular energy homeostasis. Since MROH9 is presumed to be associated with lipid metabolism and related functions, agents that alter lipid synthesis, breakdown, or signaling can exert an influence on proteins that are part of these processes. For example, 2-Deoxy-D-glucose and AICAR, by affecting glucose metabolism and activating AMPK respectively, can alter the cellular energy state, potentially influencing the activity of proteins like MROH9 that may be involved in the cellular energy response.
Compounds such as rapamycin and etomoxir can have broader effects on cellular growth and metabolism. Rapamycin, by inhibiting mTOR, modulates a key signaling pathway that orchestrates cell growth in response to nutrient availability, while etomoxir impedes fatty acid oxidation, a crucial metabolic pathway. PPAR agonists such as WY-14643, GW501516, and fenofibrate specifically target nuclear receptors that play a central role in lipid metabolism and can modulate the expression and activity of a variety of proteins within this pathway. Through these mechanisms, these chemicals can indirectly influence the function of MROH9 by altering the lipid metabolic environment within the cell. Additionally, ALLN and oligomycin, by inhibiting protein degradation and mitochondrial ATP production respectively, can affect the stability and energy regulation of proteins implicated in cellular metabolism.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
2-Deoxy-D-glucose | 154-17-6 | sc-202010 sc-202010A | 1 g 5 g | $65.00 $210.00 | 26 | |
A glycolysis inhibitor that interferes with glucose metabolism, potentially affecting proteins involved in energy sensing. | ||||||
(+)-Etomoxir sodium salt | 828934-41-4 | sc-215009 sc-215009A | 5 mg 25 mg | $148.00 $496.00 | 3 | |
Inhibits carnitine palmitoyltransferase 1 (CPT1) and can disrupt fatty acid oxidation, which may influence proteins related to lipid metabolism. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
An AMPK activator that alters cellular energy status and may indirectly affect proteins involved in metabolic regulation. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $133.00 | 7 | |
A PPARα agonist that regulates lipid metabolism and may affect proteins involved in lipid signaling pathways. | ||||||
GW501516 | 317318-70-0 | sc-202642 sc-202642A | 1 mg 5 mg | $80.00 $175.00 | 28 | |
A PPARδ agonist that can influence various aspects of lipid metabolism and related protein functions. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor that affects cell growth and metabolism, potentially affecting proteins linked to metabolic signaling. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Another PPARα agonist that modulates lipid metabolism and could indirectly influence proteins associated with lipid signaling. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $60.00 $270.00 $350.00 | 48 | |
An AMPK activator that can change cellular energy homeostasis, which may affect metabolic regulation proteins. | ||||||
Niclosamide | 50-65-7 | sc-250564 sc-250564A sc-250564B sc-250564C sc-250564D sc-250564E | 100 mg 1 g 10 g 100 g 1 kg 5 kg | $37.00 $77.00 $184.00 $510.00 $1224.00 $5814.00 | 8 | |
An oxidative phosphorylation uncoupler that can alter energy metabolism in cells, with potential effects on associated proteins. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A regulator of gene expression that can influence cell differentiation and metabolism, potentially affecting related protein functions. | ||||||