3222402P14Rik Activators
3222402P14Rik Activators encompass a series of chemical compounds that indirectly promote the functional activity of the 3222402P14Rik protein by influencing various cellular signaling pathways. Forskolin, through its ability to raise cAMP levels, indirectly supports the activation of 3222402P14Rik by activating PKA, which phosphorylates substrates that might be part of the 3222402P14Rik-associated pathways. Genistein, as a tyrosine kinase inhibitor, reduces the competition from tyrosine kinase signaling, potentially allowing for enhanced activity of pathways involving 3222402P14Rik. Sphingosine-1-phosphate and Thapsigargin operate by modulating lipid and calcium signaling pathways, respectively, which could enhance the activation of 3222402P14Rik. 3222402P14Rik Activators are a collection of chemical compounds that facilitate the activation of the 3222402P14Rik protein through the modulation of various signaling pathways.
Compounds such as Forskolin and Genistein indirectly enhance the functional activity of 3222402P14Rik by increasing cAMP levels and inhibiting tyrosine kinases, respectively. Forskolin's elevation of cAMP activates PKA, which may phosphorylate and activate 3222402P14Rik through cAMP-dependent signaling, while Genistein may enhance the activity of 3222402P14Rik by reducing the competitive activity of tyrosine kinases. Similarly, Sphingosine-1-phosphate, by binding to its receptors, may activate signaling pathways that include 3222402P14Rik as part of the sphingolipid signaling mechanism. Thapsigargin and A23187 both increase intracellular calcium levels, which could activate 3222402P14Rik through calcium-dependent pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein acts as a tyrosine kinase inhibitor. By inhibiting competing tyrosine kinase pathways, it might enhance the pathway activity in which 3222402P14Rik is involved, leading to its increased functional activation. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
Sphingosine-1-phosphate binds to its receptors which triggers a cascade of signaling events, including those that could activate the 3222402P14Rik protein through its involvement in sphingolipid signaling pathways. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin raises intracellular calcium levels by inhibiting the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), which could activate calcium-dependent signaling pathways and thus enhance the activity of 3222402P14Rik. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC) which can phosphorylate proteins in signaling pathways that may include 3222402P14Rik, leading to its activation. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG inhibits certain types of kinases, potentially reducing negative regulatory effects on pathways in which 3222402P14Rik is involved, thereby enhancing its activity. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that can alter signaling pathways, potentially leading to enhanced activity of 3222402P14Rik through indirect activation of related pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that may disrupt negative regulatory pathways, leading to an increase in 3222402P14Rik activity as a downstream effect. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 acts as an ionophore that increases intracellular calcium levels, which could enhance the activation of calcium-dependent signaling pathways involving 3222402P14Rik. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a broad-spectrum protein kinase inhibitor that may lead to the selective activation of pathways involving 3222402P14Rik by reducing the activity of inhibitory kinases. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 selectively inhibits p38 MAP kinase, which may shift the signaling equilibrium to favor the activation of pathways in which 3222402P14Rik is involved. | ||||||