2310008M10Rik Activators
Additionally, the inhibitors LY294002, U0126, and SB203580 may indirectly up-regulate 2310008M10Rik by inhibiting PI3K, MEK1/2, and p38 MAPK, respectively, thereby potentially redirecting signaling flux towards pathways where 2310008M10Rik is active or removing negative regulation. The cAMP analog 8-Bromo-cAMP acts like Forskolin by activating PKA and potentially enhancing the activity of 2310008M10Rik through phosphorylation. BIM I, by selectively inhibiting PKC isoforms, may inadvertently lead to the enhancement of 2310008M10Rik activity by redirecting signaling to 2310008M10Rik-related pathways or lifting negative PKC-mediated regulation. Lastly, Genistein, through its inhibition of tyrosine kinases, could relieve negative regulation on 2310008M10Rik, thereby increasing its activity. Collectively, these compounds work through distinct yet interconnected signaling pathways to enhance the functional activity of 2310008M10Rik without directly affecting its expression levels or requiring direct binding to the protein.
2310008M10Rik Activators encompass a variety of chemical compounds that indirectly enhance the functional activity of 2310008M10Rik through specific intracellular signaling pathways. Compounds like Forskolin and 8-Bromo-cAMP enhance intracellular cAMP levels, activating PKA, which could subsequently phosphorylate and activate downstream targets including 2310008Given the specific and nature of 2310008M10Rik Activators, these chemical compounds are proposed to indirectly augment the activity of 2310008M10Rik through their influence on distinct signaling pathways. Forskolin and 8-Bromo-cAMP, by increasing intracellular cAMP, activate protein kinase A (PKA), which could contribute to the phosphorylation and potential activation of 2310008M10Rik if it is connected to cAMP-responsive pathways.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC). Activation of PKC can lead to the phosphorylation of target proteins, potentially including 2310008M10Rik, thereby enhancing its activity through post-translational modifications. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels. Elevated calcium can activate calmodulin-dependent kinases, which may in turn activate 2310008M10Rik by phosphorylation or by influencing its interaction with other proteins in calcium-dependent signaling pathways. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG, a polyphenol found in green tea, can modulate various signaling pathways, including those involving kinases. It could enhance the activity of 2310008M10Rik by inhibiting kinases that negatively regulate 2310008M10Rik, thus indirectly increasing its activity. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
S1P is a bioactive lipid that acts through G protein-coupled receptors to activate downstream kinases. This activation can lead to phosphorylation events that may enhance the activity of 2310008M10Rik by integrating it into the signaling pathways regulated by S1P. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a specific inhibitor of PI3K. By inhibiting PI3K, it may reduce negative feedback loops and thus indirectly enhance the activity of proteins downstream or within the PI3K pathway, potentially including 2310008M10Rik. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is an inhibitor of p38 MAPK and could potentially enhance the activity of 2310008M10Rik by shifting cellular signaling away from p38 MAPK-dependent pathways toward pathways in which 2310008M10Rik is involved. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA, leading to phosphorylation events. By mimicking cAMP, it may enhance the activity of 2310008M10Rik by promoting phosphorylation-dependent activation or by altering its interactions with other signaling molecules. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is a calcium ionophore that increases intracellular calcium, similar to ionomycin. The elevation in calcium levels may activate calcium-dependent proteins and pathways potentially leading to the activation of 2310008M10Rik through phosphorylation or other regulatory mechanisms. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
BIM I is a specific inhibitor of PKC. By inhibiting certain PKC isoforms, it may indirectly enhance the activity of 2310008M10Rik by reducing negative regulatory effects exerted by PKC on the protein or by redirecting signaling flow through pathways involving 2310008M10Rik. | ||||||