1700019D03Rik Inhibitors
Chemical inhibitors of 1700019D03Rik encompass a broad spectrum of compounds that target various signaling pathways and kinases to inhibit the function of this protein. Staurosporine, a well-known protein kinase inhibitor, can impede the activity of 1700019D03Rik by directly targeting the kinases responsible for its phosphorylation and activation. Similarly, wortmannin and LY294002 focus on the PI3K pathway, a critical route for the activation of 1700019D03Rik, with both compounds effectively blocking this pathway and thus the protein's function. Rapamycin, an mTOR pathway inhibitor, can indirectly impede the action of 1700019D03Rik by inhibiting downstream signaling events crucial for the protein's role in cellular processes.
Furthermore, triciribine acts on the AKT kinase, a central player in cell survival and proliferation, to inhibit the function of 1700019D03Rik if it is part of the AKT pathway. SP600125 and lestaurtinib target the JNK and JAK2 pathways respectively, both of which could be essential for the proper functioning of 1700019D03Rik depending on its role within these signaling cascades. On another front, SB203580 and PD98059, as inhibitors of p38 MAPK and MEK respectively, can block the pathways necessary for 1700019D03Rik's function if it is regulated by either p38 MAPK or ERK signaling. U0126, also a MEK inhibitor, serves a similar function in obstructing the MEK/ERK pathway. Lastly, PP2 and dasatinib serve to inhibit Src family kinases and the BCR-ABL kinase, which can lead to the inhibition of 1700019D03Rik by targeting upstream regulatory kinases or direct interactors involved in its activation and function.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of protein kinases. Given that 1700019D03Rik is a kinase substrate, staurosporine can inhibit the phosphorylation of 1700019D03Rik by directly inhibiting the upstream kinases responsible for its activation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is an inhibitor of PI3K. Since 1700019D03Rik operates downstream of PI3K, inhibition of this kinase can result in the functional inhibition of 1700019D03Rik by preventing its activation through the PI3K signaling cascade. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is another PI3K inhibitor that can prevent the activation of 1700019D03Rik by blocking the PI3K pathway, which is required for the full functionality of 1700019D03Rik. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor that can inhibit the mTOR pathway, which is crucial for protein synthesis and cell growth. By inhibiting mTOR, rapamycin can indirectly inhibit the function of 1700019D03Rik which may be downstream of mTOR signaling. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Triciribine is an inhibitor of AKT, which is involved in cell survival and proliferation pathways. Inhibition of AKT by triciribine can lead to inhibition of 1700019D03Rik activity if 1700019D03Rik is part of the AKT signaling pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor. If 1700019D03Rik is involved in the JNK signaling pathway, inhibition of JNK by SP600125 can lead to the inhibition of 1700019D03Rik by blocking the signaling cascade required for its function. | ||||||
Lestaurtinib | 111358-88-4 | sc-218657 sc-218657A sc-218657B | 1 mg 5 mg 10 mg | $270.00 $320.00 $600.00 | 3 | |
Lestaurtinib is a JAK2 inhibitor. Since JAK2 is involved in various signaling pathways, including cytokine signaling, inhibition of JAK2 can lead to the inhibition of 1700019D03Rik by disrupting the signaling events that 1700019D03Rik requires for its activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a p38 MAPK inhibitor that can block the signaling pathway necessary for the function of 1700019D03Rik if it is involved in the p38 MAPK pathway, leading to its functional inhibition. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that can block the MEK/ERK pathway. If 1700019D03Rik is regulated by the ERK signaling pathway, PD98059 can inhibit its function by preventing the necessary signaling for 1700019D03Rik activation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is another MEK inhibitor that can inhibit the MEK/ERK pathway. If 1700019D03Rik function is dependent on this pathway, U0126 can inhibit the protein by blocking the pathway's downstream signaling. | ||||||