1700001P01Rik Inhibitors
Chemical inhibitors of 1700001P01Rik can interfere with various signaling pathways essential for the protein's activity. Staurosporine acts as a general protein kinase inhibitor, obstructing numerous kinase-dependent signaling processes that 1700001P01Rik relies on for functional engagement. Similarly, Bisindolylmaleimide I targets protein kinase C, which, if involved in the phosphorylation of 1700001P01Rik, can disrupt its state of activation or regulation. LY294002 and Wortmannin, both inhibitors of PI3K, can impede the PI3K/AKT pathway, a potential conduit for the activity of 1700001P01Rik, thereby preventing the activation of its downstream targets. This interruption can affect the functional state of 1700001P01Rik by blocking the transmission of critical signals.
In addition to the aforementioned compounds, the MEK inhibitors PD98059 and U0126 can inhibit the MEK/ERK pathway, which may be necessary for the functional activity of 1700001P01Rik. SB203580, targeting p38 MAP kinase, can disrupt signaling pathways that incorporate p38 MAPK, which are potentially critical for the functional activity of 1700001P01Rik. SP600125, as a JNK inhibitor, can obstruct JNK signaling pathways that 1700001P01Rik may require for its proper function. Rapamycin addresses the mTOR signaling, which, when inhibited, can affect the activity or regulation of 1700001P01Rik. PP2 and Dasatinib, by inhibiting Src family tyrosine kinases and BCR-ABL, can prevent the associated kinase-mediated signaling pathways from properly functioning, thereby affecting 1700001P01Rik's role in these pathways. Lastly, Y-27632, a ROCK inhibitor, can interfere with the Rho/ROCK pathway, which may have a role in the regulation or activity of 1700001P01Rik.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine inhibits a broad spectrum of protein kinases, which could lead to the functional inhibition of 1700001P01Rik by hindering kinase-dependent signaling pathways that are essential for its activity. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
This compound selectively inhibits protein kinase C, which could disrupt the phosphorylation state of 1700001P01Rik, leading to its functional inhibition if protein kinase C is directly involved in its activation or regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a PI3K inhibitor that could functionally inhibit 1700001P01Rik by blocking the PI3K/AKT pathway, which may be crucial for the protein's activity. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin inhibits PI3K, which could lead to functional inhibition of 1700001P01Rik by preventing the activation of downstream targets in the PI3K/AKT signaling pathway, directly affecting the protein's activity. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a MEK inhibitor that could lead to the functional inhibition of 1700001P01Rik by blocking the MEK/ERK pathway, which may be necessary for the protein's functional activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126, another MEK inhibitor, could functionally inhibit 1700001P01Rik by disrupting the MEK/ERK pathway, potentially involved in the regulation or activity of the protein. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 inhibits p38 MAP kinase which could functionally inhibit 1700001P01Rik by disrupting signaling pathways that rely on p38 MAPK, which are potentially critical for the protein's activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor that could lead to functional inhibition of 1700001P01Rik by blocking JNK signaling pathways that may be essential for the protein's activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR which could functionally inhibit 1700001P01Rik by disrupting mTOR signaling, which may be involved in the regulation or activity of the protein. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is an inhibitor of Src family tyrosine kinases which could functionally inhibit 1700001P01Rik by preventing Src kinase-mediated signaling pathways that are potentially involved in the protein's regulation or activity. | ||||||