Date published: 2026-10-17
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CYP1A1 Antibody (B-2) - Western Blotting - Image 13628
CYP1A1 抗体 (B-2): sc-48432. 人重组 CYP1A1 融合蛋白的 Western 印迹分析.
CYP1A1 Antibody (B-2) - Western Blotting - Image 13628
CYP1A1 抗体 (B-2): sc-48432. 人重组 CYP1A1 融合蛋白的 Western 印迹分析.
CYP1A1 抗体 (B-2): sc-48432. 人重组 CYP1A1 融合蛋白的 Western 印迹分析.

CYP1A1 抗体 (B-2): sc-48432

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寫評論提問
说明书
  • CYP1A1抗体(B-2)是小鼠单克隆IgG1 κ, 在10篇文献中引用，规格为200 µg/ml
  • 免疫human物种的CYP1A1的氨基酸246-315
  • 推荐用于 mouse, rat 和 human 来源的CYP1A1 WB, IP, IF 和 ELISA检测
  • 看 CYP1A1 (A-9): sc-393979，可查看有标记的 CYP1A1 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是CYP1A1 Antibody (B-2) for WB applications. 的首选辅助检测试剂，这些试剂现与CYP1A1 Antibody (B-2) 打包提供（请参阅下面的订购信息）。
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相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

额外CYP抗体，包括CYP11B, CYP17A1, CYP19, CYP1A1, CYP1A2, CYP1B1, CYP24, CYP26A1, CYP27A1, CYP27B1, CYP2A6, CYP2B1, CYP2C6, CYP2D6, CYP2F1和CYP2F2

P450酶是一个单加氧酶家族，参与多种内源性和外源性化合物的代谢。几种P450酶已根据序列相似性分类为CYP1A和CYP2A亚家族的成员。NADPH细胞色素P450还原酶是一种微粒体酶，在P450催化循环中负责将电子从NADPH转移到细胞色素P450酶。NADPH细胞色素P450还原酶定位于内质网，它也能将电子转移到血红素加氧酶和细胞色素b5。NADPH细胞色素P450还原酶在结构上与两个独立的黄素蛋白家族，铁氧还蛋白核苷酸还原酶（FNR）和黄素氧还蛋白有关。NADPH细胞色素P450还原酶的电子转移需要两个黄素辅因子，FAD和FMN，分别与FNR和黄素氧还蛋白结构域结合。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

CYP1A1 抗体 (B-2) 参考文献:

  1. 重金属对CYP1A1的调节及其对药物代谢的影响。  |  Anwar-Mohamed, A., et al. 2009. Expert Opin Drug Metab Toxicol. 5: 501-21. PMID: 19416086
  2. CYP1A1是miR-892a介导的转录后抑制的靶标。  |  Choi, YM., et al. 2012. Int J Oncol. 41: 331-6. PMID: 22470100
  3. CYP1A1表达和活性调节在化学预防中的作用。  |  Badal, S. and Delgoda, R. 2014. J Appl Toxicol. 34: 743-53. PMID: 24532440
  4. 细胞色素P450 1A1（CYP1A1）基因多态性与乳腺癌易感性：中国人群荟萃分析。  |  Wu, H., et al. 2017. Clin Lab. 63: 67-72. PMID: 28164497
  5. CYP1A1代谢调节：从不良健康影响到化学预防和治疗选择。  |  Mescher, M. and Haarmann-Stemmann, T. 2018. Pharmacol Ther. 187: 71-87. PMID: 29458109
  6. 大肠癌中PAH代谢酶CYP1A1的多态性及其与临床病理的相关性。  |  Cheng, T., et al. 2022. Pathol Res Pract. 231: 153801. PMID: 35180652
  7. CYP1A1是诊断软组织血管纤维瘤的有用标记物。  |  Uemura, K., et al. 2023. Am J Surg Pathol. 47: 547-557. PMID: 36876749
  8. 从重组CYP1A1到人类的底物固有清除率的定量翻译。  |  Di, L. 2023. AAPS J. 25: 98. PMID: 37798423
  9. CYP1A1免疫组化对软组织血管纤维瘤的形态学模拟具有高度特异性。  |  Bauer, AH., et al. 2024. Histopathology. 84: 381-386. PMID: 37855220
  10. CYP1A1基因与癌症易感性。  |  Kawajiri, K., et al. 1993. Crit Rev Oncol Hematol. 14: 77-87. PMID: 8103989

订购信息

产品名称产品编号规格价格数量收藏夹

CYP1A1 抗体 (B-2)

sc-48432
200 µg/ml
$322.00

CYP1A1 (B-2): m-IgG Fc BP-HRP 套装

sc-553104
200 µg Ab; 10 µg BP
$361.00

CYP1A1 (B-2): m-IgG1 BP-HRP 套装

sc-553105
200 µg Ab; 20 µg BP
$361.00

Is there any intercross between cyp1a1 and cyp1a2 by western blot in mouse?

Asked by: Anonymous
Thank you for your question. This CYP1A1 (B-2) antibody, sc-48432, is specific for cyp1a1 and will not detect cyp1a2 in a Western blot.
Answered by: Tech Service
Date published: 2019-10-29

I need to use an antibody to detect the protein in samples of avian origin. Do you know if sc-48432: CYP1A1 (B-2) mouse monoclonal antibody will work?

Asked by: Dr Ninau Qelp
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 5 out of 5 by LF from Good WB antibody in normal human epidermalGood WB antibody in normal human epidermal keratinocytes (NHEKs). -SCBT Publication Review
Date published: 2015-05-12
Rated 5 out of 5 by JT from Good staining in IF in human synovial tissueGood staining in IF in human synovial tissue. -SCBT Publication Review
Date published: 2015-04-26
Rated 5 out of 5 by SM from Strong band in WB in human recombinant CYP1A1Strong band in WB in human recombinant CYP1A1 fusion protein. -SCBT QC
Date published: 2015-01-24
Rated 5 out of 5 by JL from Works well in IF in human induced pluripotentWorks well in IF in human induced pluripotent stem cells. -SCBT Publication Review
Date published: 2013-11-17
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CYP1A1 抗体 (B-2) is rated 5.0 out of 5 by 4.
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