TRAF4 Activators
TRAF4 activators encompass a diverse range of chemicals that selectively modulate the activity of TRAF4, a crucial signaling adaptor protein. Honokiol, for instance, indirectly activates TRAF4 by inhibiting NF-κB signaling. Through the suppression of IκBα phosphorylation, Honokiol influences the NF-κB pathway, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. Betulinic acid activates TRAF4 indirectly by enhancing the apoptotic pathway. Through modulation of Bcl-2 family proteins, Betulinic acid influences TRAF4 activation, impacting downstream signaling events associated with apoptotic regulation. Nordihydroguaiaretic acid (NDGA) indirectly activates TRAF4 by inhibiting reactive oxygen species (ROS) production. By reducing oxidative stress, NDGA influences cellular redox status, leading to indirect activation of TRAF4 and modulation of cellular processes associated with oxidative stress. Withaferin A activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through the suppression of p65 nuclear translocation, Withaferin A modulates NF-κB signaling, leading to indirect activation of TRAF4 and influencing downstream cellular processes.
Luteolin activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, Luteolin modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. Ursolic acid activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through modulation of IκBα degradation, Ursolic acid influences NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. EGCG (Epigallocatechin gallate) activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, EGCG modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. Cryptotanshinone activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through modulation of IκBα degradation, Resveratrol influences NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. Collectively, these activators provide a valuable toolkit for researchers to selectively modulate TRAF4 activity, offering insights into the intricate regulation of cellular responses associated with TRAF4 activation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Honokiol | 35354-74-6 | sc-202653 sc-202653A | 10 mg 25 mg | $118.00 $178.00 | 4 | |
Honokiol activates TRAF4 indirectly by inhibiting NF-κB signaling. Through suppression of IκBα phosphorylation, Honokiol modulates the NF-κB pathway, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Betulinic acid activates TRAF4 indirectly by enhancing the apoptotic pathway. Through modulation of Bcl-2 family proteins, Betulinic acid influences TRAF4 activation, impacting downstream signaling events associated with apoptotic regulation. | ||||||
NDGA (Nordihydroguaiaretic acid) | 500-38-9 | sc-200487 sc-200487A sc-200487B | 1 g 5 g 25 g | $109.00 $384.00 $2190.00 | 3 | |
NDGA activates TRAF4 indirectly by inhibiting reactive oxygen species (ROS) production. By reducing oxidative stress, NDGA influences cellular redox status, leading to indirect activation of TRAF4 and modulation of cellular processes associated with oxidative stress. | ||||||
Withaferin A | 5119-48-2 | sc-200381 sc-200381A sc-200381B sc-200381C | 1 mg 10 mg 100 mg 1 g | $130.00 $583.00 $4172.00 $20506.00 | 20 | |
Withaferin A activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of p65 nuclear translocation, Withaferin A modulates NF-κB signaling, leading to indirect activation of TRAF4 and influencing downstream cellular processes. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, Luteolin modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $56.00 $180.00 | 8 | |
Ursolic acid activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through modulation of IκBα degradation, Ursolic acid influences NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, EGCG modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
Cryptotanshinone | 35825-57-1 | sc-280649 | 10 mg | $119.00 | 1 | |
Cryptotanshinone activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, Cryptotanshinone modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through modulation of IκBα degradation, Resveratrol influences NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $82.00 $204.00 | 5 | |
Hesperidin activates TRAF4 indirectly by inhibiting the NF-κB pathway. Through suppression of IκBα phosphorylation, Hesperidin modulates NF-κB signaling, leading to indirect activation of TRAF4 and modulation of downstream cellular processes. | ||||||