SPDSY Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
N-(3-Aminopropyl)cyclohexylamine | 3312-60-5 | sc-202715 sc-202715D sc-202715A sc-202715B sc-202715C | 1 g 5 g 10 g 25 g 100 g | $37.00 $43.00 $52.00 $67.00 $213.00 | 3 | |
N-(3-Aminopropyl)cyclohexylamine acts as a specialized SPDSY, characterized by its ability to engage in unique hydrogen bonding and steric interactions due to its cyclohexyl structure. This compound exhibits notable reactivity through its amine functional group, facilitating nucleophilic attacks in various chemical pathways. Its conformational flexibility enhances molecular interactions, allowing for tailored reactivity in diverse environments, influencing both kinetics and selectivity in reactions. | ||||||
Difluoromethylornithine | 70052-12-9 | sc-204723 sc-204723A sc-204723B sc-204723C sc-204723D sc-204723E | 10 mg 25 mg 100 mg 250 mg 1 g 5 g | $59.00 $133.00 $161.00 $317.00 $983.00 $4821.00 | 2 | |
Inhibits ornithine decarboxylase, the rate-limiting enzyme in polyamine biosynthesis, reducing SPDSY substrate availability. | ||||||
Diminazene Aceturate | 908-54-3 | sc-205651 sc-205651A | 1 g 5 g | $92.00 $377.00 | 11 | |
Intercalates DNA, reduces transcription of SPDSY, hence directly affecting the enzyme concentration in the cell. | ||||||
N1,N11-Diethylnorspermine tetrahydrochloride | 156886-85-0 | sc-204114 sc-204114A sc-204114B | 1 mg 5 mg 10 mg | $148.00 $611.00 $1219.00 | 6 | |
Causes upregulation of spermidine/spermine N1-acetyltransferase (SSAT), increasing SPDSY substrate acetylation and depletion. | ||||||
MDL 72527 | 93565-01-6 | sc-295375C sc-295375B sc-295375 sc-295375D sc-295375A | 1 mg 5 mg 10 mg 25 mg 50 mg | $45.00 $132.00 $201.00 $391.00 $750.00 | ||
Inhibits polyamine oxidase, affecting back-conversion of spermine to spermidine, thereby altering SPDSY substrate levels. | ||||||
Pentamidine | 100-33-4 | sc-208158 sc-208158A | 25 mg 50 mg | $380.00 $568.00 | ||
Disrupts mitochondrial function leading to decreased ATP levels, which indirectly inhibits SPDSY by affecting substrate binding. | ||||||
Cyclohexylamine | 108-91-8 | sc-239615 | 25 ml | $21.00 | ||
Competitive inhibitor that directly binds to the SPDSY active site, preventing substrate binding. | ||||||
Diethyl Pyrocarbonate | 1609-47-8 | sc-202574B sc-202574 sc-202574A | 5 g 25 g 100 g | $61.00 $138.00 $478.00 | 1 | |
Directly modifies His residues crucial for SPDSY activity, inhibiting its enzymatic function. | ||||||