Diminazene Aceturate CAS: 908-54-3
MF: C22H29N9O6
MW: 515.52
An anti-protozoal and anti-trypanosomal compound.

Diminazene Aceturate (CAS 908-54-3)

Diminazene Aceturate | CAS 908-54-3 is rated 5.0 out of 5 by 1.
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Alternate Names: Azidin; Berenil
Application: Diminazene Aceturate is an anti-protozoal and anti-trypanosomal compound
CAS Number: 908-54-3
Purity: ≥97%
Molecular Weight: 515.52
Molecular Formula: C22H29N9O6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Diminazene Aceturate has anti-protozoal and anti-trypanosomal properties. Diminazene Aceturate is an activator of ACE2.


References

1. Gilbert, R.J. 1983. Brit. J. Pharmacol. 80: 133-139. PMID: 6652366
2. Diack, A., et al. 1997. Vet. Parisitol. 70: 13-23. PMID: 9195705

Physical State :
Solid
Solubility :
Soluble in water (50 mg/ml), methanol, DMSO, and alcohol (slightly).
Storage :
Store at room temperature
Melting Point :
219-228° C
Refractive Index :
n20D 1.71 (Predicted)
IC50 :
Trypanosoma brucei brucei: IC50 = 3 nM; Trypanosoma brucei rhodesiense: IC50 = 8.9 µM; Babesia gibsoni: IC50 = 0.10 µg/ml; Calf thymus DNA: IC50 = 59 µg/ml (bovine); Nucleic Acid: IC50 = 67 µg/ml
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
MB7605000
PubChem CID :
5284544
Merck Index :
14: 3266
MDL Number :
MFCD00058386
EC Number :
212-999-2
SMILES :
CC(=O)NCC(=O)O.CC(=O)NCC(=O)O.C1=CC(=CC=C1C(=N)N)NN=NC2=CC=C(C=C2)C(=N)N

Download SDS (MSDS)

Certificate of Analysis

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Diminazene Aceturate (CAS 908-54-3)  Product Citations

See how others have used Diminazene Aceturate (CAS 908-54-3). Click on the entry to view the PubMed entry .

Citations 1 to 3 of 3 total

PMID: # 26862037  2016. J Neuroinflammation. 13: 35.

PMID: # 26344166  Zsila, F. et al. 2015. Phys Chem Chem Phys. 17: 24560-5.

PMID: # 21436312  Teka, IA. et al. 2011. Mol. Pharmacol. 80: 110-116.

Citations 1 to 3 of 3 total

Is this light sensitive when solubilize?

Asked by: Priya Tiwari
Thank you for your question. No, this material is not light sensitive.
Answered by: Technical Support
Date published: 2018-12-27
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Rated 5 out of 5 by from Foureaux Foureaux, G. et al. (PubMed 26204514) evaluated the effects of chitosan inserts for sustained release of the angiotensin-converting enzyme 2 (ACE2) activator, Diminazene Aceturate (DIZE), in experimental glaucoma. No toxic effects in the eyes related to application of the inserts were observed. Moreover, biodistribution studies showed prolonged retention of DIZE in the corneal site. -SCBT Publication Review
Date published: 2015-01-04
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