Date published: 2025-10-26

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Prion Protein Antibodies

Santa Cruz Biotechnology provides a broad selection of Prion Protein monoclonal antibodies for various research applications. Prion Protein Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Prion proteins play a critical role in neurodegenerative diseases, including Creutzfeldt-Jakob disease and other transmissible spongiform encephalopathies. The misfolding and aggregation of prion proteins can lead to severe neurological damage, making prion protein research essential for understanding disease mechanisms and developing potential therapeutic strategies. The ability to accurately detect and analyze prion proteins is crucial for advancing research in this field. Prion protein monoclonal antibodies enable researchers to investigate protein expression patterns, cellular localization, and protein-protein interactions. Prion Protein Antibodies targeting prion proteins support detailed molecular studies of neurodegenerative processes. Santa Cruz Biotechnology monoclonal antibodies for prion protein research contribute to advancing scientific understanding of neurodegenerative diseases and potential therapeutic developments.

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Prion Protein Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

PrP Antibody (5B2)

sc-47730mouse IgG1 κFL (m)WB, IP, IF, IHC(P), FCM, ELISAmammalian
5
(5)

PrP Antibody (8B4)

sc-47729mouse IgG1 κFL (m)WB, IP, IF, IHC(P), FCM, ELISAmammalian
17
(4)

PrP Antibody (AH6)

sc-69896mouse IgG2a κFL (ovine)WB, IP, FCM, ELISAm, r, h, ovine, hamster and deer
4
(3)

PrP Antibody (6G3)

sc-52969mouse IgG1130-150 (h)WB, IPm, r, h, bovine, ovine and deer

new

(2)

PrP Antibody (G-12)

sc-398451mouse IgG1 κ217-232 (h)WB, IP, IF, ELISAm, r, h
1
(2)

PrP Antibody (H-8)

sc-393165mouse IgG2a κ1-253 (h)WB, IP, IF, IHC(P), ELISAh
1
(3)

Prion Protein CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PrP CRISPR/Cas9 KO Plasmid (h2)

sc-401061-KO-2hGene KnockoutGFP0
(0)

PrP HDR Plasmid (h2)

sc-401061-HDR-2hHomology Directed RepairPuromycin0
(0)

PrP Double Nickase Plasmid (h)

sc-401061-NIChGene KnockoutPuromycin0
(0)

PrP Double Nickase Plasmid (h2)

sc-401061-NIC-2hGene KnockoutPuromycin0
(0)

PrP CRISPR/Cas9 KO Plasmid (m2)

sc-422422-KO-2mGene KnockoutGFP0
(0)

PrP HDR Plasmid (m2)

sc-422422-HDR-2mHomology Directed RepairPuromycin0
(0)

PrP Double Nickase Plasmid (m)

sc-422422-NICmGene KnockoutPuromycin0
(0)

PrP Double Nickase Plasmid (m2)

sc-422422-NIC-2mGene KnockoutPuromycin0
(0)

Prion Protein CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PrP CRISPR Activation Plasmid (h)

sc-401061-ACThGene ActivationPuro, Blast, Hygro0
(0)

PrP CRISPR Activation Plasmid (h2)

sc-401061-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

PrP Lentiviral Activation Particles (h)

sc-401061-LAChGene ActivationPuro, Blast, Hygro0
(0)

PrP Lentiviral Activation Particles (h2)

sc-401061-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

PrP CRISPR Activation Plasmid (m)

sc-422422-ACTmGene ActivationPuro, Blast, Hygro0
(0)

PrP CRISPR Activation Plasmid (m2)

sc-422422-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

PrP Lentiviral Activation Particles (m)

sc-422422-LACmGene ActivationPuro, Blast, Hygro0
(0)

PrP Lentiviral Activation Particles (m2)

sc-422422-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Prion Protein siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

PrP siRNA (h)

sc-36318hGene SilencingN/A
11
(0)

PrP shRNA Plasmid (h)

sc-36318-SHhGene SilencingPuromycin
11
(0)

PrP shRNA (h) Lentiviral Particles

sc-36318-VhGene SilencingPuromycin
11
(0)

PrP siRNA (m)

sc-36319mGene SilencingN/A
2
(0)

PrP shRNA Plasmid (m)

sc-36319-SHmGene SilencingPuromycin
2
(0)

PrP shRNA (m) Lentiviral Particles

sc-36319-VmGene SilencingPuromycin
2
(0)