Date published: 2026-7-23

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IL-17 Antibodies

Santa Cruz Biotechnology provides a broad selection of IL-17 monoclonal antibodies for research in understanding IL-17's role in various biological processes. IL-17 monoclonal antibodies are suitable for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). IL-17 is a pro-inflammatory cytokine that plays a crucial role in the immune response, particularly in the pathogenesis of autoimmune diseases and chronic inflammatory conditions. IL-17 is primarily produced by T helper 17 (Th17) cells and is involved in the recruitment of neutrophils and the activation of other immune cells. Understanding IL-17 function is essential for developing targeted therapies for diseases such as rheumatoid arthritis, psoriasis, and multiple sclerosis. IL-17 monoclonal antibodies enable researchers to explore immune system regulation and inflammatory responses in detail. Studying IL-17 signaling pathways helps advance knowledge about immune cell communication and tissue inflammation. IL-17 research contributes to understanding both normal immune function and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in advancing scientific understanding of immune system regulation and developing new therapeutic approaches.

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IL-17 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

IL-17 Antibody (G-4)

sc-374218mouse IgG2a κ111-140 (h)WB, IP, IF, ELISAm, r, h
56
(18)

IL-17 Antibody (TC11-18H10)

sc-52567rat IgG1FL (m)WB, IP, IF, FCM, ELISAm
6
(2)

IL-17 Antibody (1)

sc-53937mouse IgG2b κFL (h)WB, ELISAh
1
(1)

IL-17E Antibody (4H194)

sc-71342mouse IgG2b115-132 (h)WBm, r, h

new

(1)

IL-17E Antibody (68C1039)

sc-52933mouse IgG2b115-132 (h)WBm, r, h
1
(2)

IL-17E Antibody (30479)

sc-74175mouse IgG1FL (h)WB, FCM, ELISAm, r, h

new

(1)

IL-17F Antibody (D-2)

sc-514191mouse IgG2a κ27-77 (m)WB, IP, IF, ELISAm, r
1
(1)

IL-17F Antibody (G-6)

sc-515029mouse IgG1 κ29-80 (h)WB, IP, IF, ELISAh

new

(1)

IL-17RB Antibody (TJ-5)

sc-73969rat IgG2b(m)WB, IPm
1
(3)

IL-17 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

IL-17 siRNA (h)

sc-39649hGene SilencingN/A
1
(0)

IL-17 shRNA Plasmid (h)

sc-39649-SHhGene SilencingPuromycin
1
(0)

IL-17 shRNA (h) Lentiviral Particles

sc-39649-VhGene SilencingPuromycin
1
(0)

IL-17 siRNA (m)

sc-39650mGene SilencingN/A
4
(0)

IL-17 shRNA Plasmid (m)

sc-39650-SHmGene SilencingPuromycin
4
(0)

IL-17 shRNA (m) Lentiviral Particles

sc-39650-VmGene SilencingPuromycin
4
(0)

IL-17B siRNA (h)

sc-39651hGene SilencingN/A0
(0)

IL-17B shRNA Plasmid (h)

sc-39651-SHhGene SilencingPuromycin0
(0)

IL-17B shRNA (h) Lentiviral Particles

sc-39651-VhGene SilencingPuromycin0
(0)

IL-17B siRNA (m)

sc-39652mGene SilencingN/A0
(0)

IL-17B shRNA Plasmid (m)

sc-39652-SHmGene SilencingPuromycin0
(0)

IL-17B shRNA (m) Lentiviral Particles

sc-39652-VmGene SilencingPuromycin0
(0)

IL-17C siRNA (h)

sc-39653hGene SilencingN/A
3
(0)

IL-17C shRNA Plasmid (h)

sc-39653-SHhGene SilencingPuromycin
3
(0)

IL-17C shRNA (h) Lentiviral Particles

sc-39653-VhGene SilencingPuromycin
3
(0)

IL-17D siRNA (h)

sc-105565hGene SilencingN/A0
(0)

IL-17D shRNA Plasmid (h)

sc-105565-SHhGene SilencingPuromycin0
(0)

IL-17D shRNA (h) Lentiviral Particles

sc-105565-VhGene SilencingPuromycin0
(0)

IL-17E siRNA (h)

sc-39654hGene SilencingN/A0
(0)

IL-17E shRNA Plasmid (h)

sc-39654-SHhGene SilencingPuromycin0
(0)

IL-17E shRNA (h) Lentiviral Particles

sc-39654-VhGene SilencingPuromycin0
(0)

IL-17E siRNA (m)

sc-39655mGene SilencingN/A0
(0)

IL-17E shRNA Plasmid (m)

sc-39655-SHmGene SilencingPuromycin0
(0)

IL-17E shRNA (m) Lentiviral Particles

sc-39655-VmGene SilencingPuromycin0
(0)

IL-17F siRNA (h)

sc-39656hGene SilencingN/A0
(0)

IL-17F shRNA Plasmid (h)

sc-39656-SHhGene SilencingPuromycin0
(0)

IL-17F shRNA (h) Lentiviral Particles

sc-39656-VhGene SilencingPuromycin0
(0)

IL-17F siRNA (m)

sc-146204mGene SilencingN/A
1
(0)

IL-17F shRNA Plasmid (m)

sc-146204-SHmGene SilencingPuromycin
1
(0)

IL-17F shRNA (m) Lentiviral Particles

sc-146204-VmGene SilencingPuromycin
1
(0)

IL-17RB siRNA (h)

sc-39964hGene SilencingN/A
1
(0)

IL-17RB shRNA Plasmid (h)

sc-39964-SHhGene SilencingPuromycin
1
(0)

IL-17RB shRNA (h) Lentiviral Particles

sc-39964-VhGene SilencingPuromycin
1
(0)

IL-17RB siRNA (m)

sc-39965mGene SilencingN/A0
(0)

IL-17RB shRNA Plasmid (m)

sc-39965-SHmGene SilencingPuromycin0
(0)

IL-17RB shRNA (m) Lentiviral Particles

sc-39965-VmGene SilencingPuromycin0
(0)

IL-17RC siRNA (h)

sc-78333hGene SilencingN/A
1
(0)

IL-17RC shRNA Plasmid (h)

sc-78333-SHhGene SilencingPuromycin
1
(0)

IL-17RC shRNA (h) Lentiviral Particles

sc-78333-VhGene SilencingPuromycin
1
(0)

IL-17RC siRNA (m)

sc-146205mGene SilencingN/A0
(0)

IL-17RC shRNA Plasmid (m)

sc-146205-SHmGene SilencingPuromycin0
(0)

IL-17RC shRNA (m) Lentiviral Particles

sc-146205-VmGene SilencingPuromycin0
(0)

IL-17RD siRNA (h)

sc-78429hGene SilencingN/A0
(0)

IL-17RD shRNA Plasmid (h)

sc-78429-SHhGene SilencingPuromycin0
(0)

IL-17RD shRNA (h) Lentiviral Particles

sc-78429-VhGene SilencingPuromycin0
(0)

IL-17RD siRNA (m)

sc-146206mGene SilencingN/A0
(0)

IL-17RD shRNA Plasmid (m)

sc-146206-SHmGene SilencingPuromycin0
(0)

IL-17RD shRNA (m) Lentiviral Particles

sc-146206-VmGene SilencingPuromycin0
(0)

IL-17RE siRNA (h)

sc-78345hGene SilencingN/A
2
(0)

IL-17RE shRNA Plasmid (h)

sc-78345-SHhGene SilencingPuromycin
2
(0)

IL-17RE shRNA (h) Lentiviral Particles

sc-78345-VhGene SilencingPuromycin
2
(0)

IL-17RE siRNA (m)

sc-146207mGene SilencingN/A0
(0)

IL-17RE shRNA Plasmid (m)

sc-146207-SHmGene SilencingPuromycin0
(0)

IL-17RE shRNA (m) Lentiviral Particles

sc-146207-VmGene SilencingPuromycin0
(0)

IL-17REL siRNA (h)

sc-75032hGene SilencingN/A0
(0)

IL-17REL shRNA Plasmid (h)

sc-75032-SHhGene SilencingPuromycin0
(0)

IL-17REL shRNA (h) Lentiviral Particles

sc-75032-VhGene SilencingPuromycin0
(0)

IL-17 CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

IL-17 CRISPR/Cas9 KO Plasmid (h2)

sc-400293-KO-2Gene Knockouth0
(0)

IL-17 CRISPR/Cas9 KO Plasmid (m)

sc-421092Gene Knockoutm0
(0)

IL-17 HDR Plasmid (m)

sc-421092-HDRHomology Directed Repairm0
(0)

IL-17RB CRISPR/Cas9 KO Plasmid (h)

sc-404114Gene Knockouth0
(0)

IL-17RB HDR Plasmid (h)

sc-404114-HDRHomology Directed Repairh0
(0)

IL-17RB CRISPR/Cas9 KO Plasmid (m)

sc-424524Gene Knockoutm0
(0)

IL-17RB HDR Plasmid (m)

sc-424524-HDRHomology Directed Repairm0
(0)

IL-17RC CRISPR/Cas9 KO Plasmid (h)

sc-403559Gene Knockouth0
(0)

IL-17RC HDR Plasmid (h)

sc-403559-HDRHomology Directed Repairh0
(0)

IL-17RC CRISPR/Cas9 KO Plasmid (m)

sc-431348Gene Knockoutm0
(0)

IL-17RC HDR Plasmid (m)

sc-431348-HDRHomology Directed Repairm0
(0)

IL-17RD CRISPR/Cas9 KO Plasmid (h2)

sc-405362-KO-2Gene Knockouth20
(0)

IL-17RD HDR Plasmid (h2)

sc-405362-HDR-2Homology Directed Repairh20
(0)

IL-17RD CRISPR/Cas9 KO Plasmid (m)

sc-431369Gene Knockoutm0
(0)

IL-17RD HDR Plasmid (m)

sc-431369-HDRHomology Directed Repairm0
(0)

IL-17RE CRISPR/Cas9 KO Plasmid (h)

sc-405190Gene Knockouth0
(0)

IL-17RE HDR Plasmid (h)

sc-405190-HDRHomology Directed Repairh0
(0)

IL-17 CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

IL-17 Double Nickase Plasmid (h)

sc-400293-NICGene Knockouth0
(0)

IL-17 Double Nickase Plasmid (h2)

sc-400293-NIC-2Gene Knockouth0
(0)

IL-17 Double Nickase Plasmid (m)

sc-421092-NICGene Knockoutm0
(0)

IL-17 Double Nickase Plasmid (m2)

sc-421092-NIC-2Gene Knockoutm0
(0)

IL-17RE Double Nickase Plasmid (h)

sc-405190-NICGene Knockouth0
(0)

IL-17RE Double Nickase Plasmid (h2)

sc-405190-NIC-2Gene Knockouth0
(0)

IL-17 CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

IL-17 CRISPR Activation Plasmid (h)

sc-400293-ACTGene Activationh0
(0)

IL-17 CRISPR Activation Plasmid (h2)

sc-400293-ACT-2Gene Activationh0
(0)

IL-17 CRISPR Activation Plasmid (m)

sc-421092-ACTGene Activationm0
(0)

IL-17 CRISPR Activation Plasmid (m2)

sc-421092-ACT-2Gene Activationm0
(0)

IL-17RB CRISPR Activation Plasmid (h)

sc-404114-ACTGene Activationh0
(0)

IL-17RD CRISPR Activation Plasmid (h)

sc-405362-ACTGene Activationh0
(0)

IL-17RD CRISPR Activation Plasmid (h2)

sc-405362-ACT-2Gene Activationh0
(0)