ZNF784 Antibody (B-8): sc-514381
- ZNF784 Antibody (B-8) is a mouse monoclonal IgG1 κ ZNF784 antibody provided at 200 µg/ml
- raised against amino acids 41-89 mapping near the N-terminus of ZNF784 of human origin
- ZNF784 Antibody (B-8) is recommended for detection of ZNF784 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZNF784 Antibody (B-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF784 Antibody (B-8) for WB applications. These reagents are now offered in bundles with ZNF784 Antibody (B-8) (see ordering information below).
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ZNF784 Antibody (B-8) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZNF784 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF784 Antibody (B-8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF784, consisting of 323 amino acids, is a member of the Krüppel C2H2-type zinc-finger protein family and features six C2H2-type zinc fingers, which are critical for DNA binding and transcriptional regulation. Located primarily in the nucleus, ZNF784 plays a significant role in modulating gene expression, essential for various cellular processes, including development and differentiation. ZNF784 is encoded by a gene located on human chromosome 19q13.42, and interaction with other proteins, such as KAP1, suggests recruitment of histone-modifying enzymes to regulate chromatin structure and gene accessibility. This regulatory mechanism maintains proper cellular function and responds to environmental signals, making ZNF784 an important target for research in gene regulation and potential therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF784 Antibody (B-8) References:
- Comparative analysis of KRAB zinc finger proteins in rodents and man: evidence for several evolutionarily distinct subfamilies of KRAB zinc finger genes. | Mark, C., et al. 1999. DNA Cell Biol. 18: 381-96. PMID: 10360839
- The zinc finger-associated SCAN box is a conserved oligomerization domain. | Williams, AJ., et al. 1999. Mol Cell Biol. 19: 8526-35. PMID: 10567577
- Biochemical analysis of the Kruppel-associated box (KRAB) transcriptional repression domain. | Peng, H., et al. 2000. J Biol Chem. 275: 18000-10. PMID: 10748030
- KRAB-containing zinc-finger repressor proteins. | Urrutia, R. 2003. Genome Biol. 4: 231. PMID: 14519192
- A comprehensive catalog of human KRAB-associated zinc finger genes: insights into the evolutionary history of a large family of transcriptional repressors. | Huntley, S., et al. 2006. Genome Res. 16: 669-77. PMID: 16606702
- [Progress in the study of KRAB zinc finger protein]. | Tian, CY., et al. 2006. Yi Chuan. 28: 1451-6. PMID: 17098717
- The Krüppel-associated box-A (KRAB-A) domain of zinc finger proteins mediates transcriptional repression. | Witzgall, R., et al. 1994. Proc Natl Acad Sci U S A. 91: 4514-8. PMID: 8183940
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF784 Antibody (B-8) | sc-514381 | 200 µg/ml | $316.00 | |||
ZNF784 Antibody (B-8): m-IgG Fc BP-HRP Bundle | sc-531103 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZNF784 Antibody (B-8): m-IgGκ BP-HRP Bundle | sc-524701 | 200 µg Ab, 40 µg BP | $354.00 | |||
ZNF784 Antibody (B-8) AC | sc-514381 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZNF784 Antibody (B-8) HRP | sc-514381 HRP | 200 µg/ml | $316.00 | |||
ZNF784 Antibody (B-8) FITC | sc-514381 FITC | 200 µg/ml | $330.00 | |||
ZNF784 Antibody (B-8) PE | sc-514381 PE | 200 µg/ml | $343.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 488 | sc-514381 AF488 | 200 µg/ml | $357.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 546 | sc-514381 AF546 | 200 µg/ml | $357.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 594 | sc-514381 AF594 | 200 µg/ml | $357.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 647 | sc-514381 AF647 | 200 µg/ml | $357.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 680 | sc-514381 AF680 | 200 µg/ml | $357.00 | |||
ZNF784 Antibody (B-8) Alexa Fluor® 790 | sc-514381 AF790 | 200 µg/ml | $357.00 |