ZFAND2B Antibody (A-11): sc-514674

ZFAND2B Antibody (A-11) is a mouse monoclonal IgG1 antibody that detects ZFAND2B in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZFAND2B, also known as AN1-type zinc finger protein 2B, is a 257 amino acid protein characterized by two AN1-type zinc fingers and two ubiquitin-interacting motif repeats, which play a crucial role in the ubiquitination pathway. The presence of the AN1-type zinc finger domain suggests ZFAND2B involvement in protein degradation regulation and cellular signaling, making ZFAND2B essential for maintaining cellular homeostasis and responding to stress. ZFAND2B interactions with various proteins, including those involved in the ubiquitin-proteasome system, highlight ZFAND2B importance in modulating protein turnover and influencing various cellular processes. Two isoforms of ZFAND2B, resulting from alternative splicing, further emphasize the complexity of ZFAND2B function and regulation, as these isoforms may have distinct roles in cellular mechanisms. With versatile applications and significant biological relevance, anti-ZFAND2B antibody (A-11) serves as an invaluable tool for researchers studying zinc-finger proteins and their impact on cellular functions.

The preferred ZFAND2B antibody is ZFAND2B Antibody (D-2): sc-398000.