
ZAG Antibody (G-8) is a mouse monoclonal IgG1 antibody that detects ZAG (Zn-α2-glycoprotein) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZAG is a soluble, secreted protein predominantly found in serum and various body fluids, including cerebrospinal fluid, blood plasma, urine, and sweat. Notably, ZAG plays a crucial role in lipid metabolism, as ZAG stimulates lipid degradation in adipocytes, which is significant for maintaining energy homeostasis in the body. ZAG overexpression has been linked to extensive fat losses observed in advanced cancers, highlighting ZAG′s potential as a biomarker for cachexia and metabolic disorders. The structure of ZAG features a large groove similar to the peptide binding grooves of class I major histocompatibility complex (MHC) proteins, although ZAG does not bind the class I light chain β-2-Microglobulin. This unique structural characteristic may influence ZAG′s interactions and functions within the immune system and metabolic pathways. Anti-ZAG antibody (G-8) is an essential tool for researchers investigating ZAG′s roles in health and disease, providing valuable insights into ZAG′s function and potential therapeutic applications.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZAG Antibody (G-8) | sc-166701 | 200 µg/ml | $322.00 | |||
ZAG Antibody (G-8): m-IgG Fc BP-HRP Bundle | sc-537523 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZAG Antibody (G-8): m-IgGκ BP-HRP Bundle | sc-534814 | 200 µg Ab; 40 µg BP | $361.00 | |||
ZAG Antibody (G-8): m-IgG1 BP-HRP Bundle | sc-545212 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZAG (G-8) Neutralizing Peptide | sc-166701 P | 100 µg/0.5 ml | $69.00 |