WDR78 Antibody (E-7): sc-390633
- WDR78 Antibody (E-7) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 459-482 within an internal region of WDR78 isoforms of human origin
- recommended for detection of WDR78 isoforms of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for WDR78 Antibody (E-7) for WB applications. These reagents are now offered in bundles with WDR78 Antibody (E-7) (see ordering information below).
WDR78 (E-7) is a mouse monoclonal IgG1 antibody. WD-repeats are motifs found in various proteins, characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins containing WD-repeats participate in diverse cellular functions, these proteins generally involve regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR78 (WD repeat domain 78) contains six WD repeats and exists as three alternatively spliced isoforms, spanning 848 amino acids. WDR78 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
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WDR78 Antibody (E-7) References:
- ZRANB2 localizes to supraspliceosomes and influences the alternative splicing of multiple genes in the transcriptome. | Yang, YH., et al. 2013. Mol Biol Rep. 40: 5381-95. PMID: 23666063
- Temporal endogenous gene expression profiles in response to polymer-mediated transfection and profile comparison to lipid-mediated transfection. | Martin, TM., et al. 2015. J Gene Med. 17: 33-53. PMID: 25663627
- Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. | Zhang, Y., et al. 2019. J Mol Cell Biol. 11: 383-394. PMID: 30060180
- Whole exome sequencing analyses reveal gene-microbiota interactions in the context of IBD. | Hu, S., et al. 2021. Gut. 70: 285-296. PMID: 32651235
- Molecular insights into the development of hepatic metastases in colorectal cancer: a metastasis prediction study. | Yang, J., et al. 2020. Eur Rev Med Pharmacol Sci. 24: 12701-12708. PMID: 33378017
- Bi-allelic variants in human WDR63 cause male infertility via abnormal inner dynein arms assembly. | Lu, S., et al. 2021. Cell Discov. 7: 110. PMID: 34782613
- Microarray and bioinformatic analysis reveal the parental genes of m6A modified circRNAs as novel prognostic signatures in colorectal cancer. | Liang, W., et al. 2022. Front Oncol. 12: 939790. PMID: 35965538
- Tanreqing suppresses the proliferation and migration of non-small cell lung cancer cells by mediating the inactivation of the HIF1α signaling pathway via exosomal circ-WDR78. | Hong, W., et al. 2025. J Biomol Struct Dyn. 43: 2491-2502. PMID: 38247231
- Construction and validation of a ubiquitination-related prognostic risk score signature in breast cancer. | Feng, K., et al. 2024. Heliyon. 10: e35553. PMID: 39170352
- TCTEX1D2 is essential for sperm flagellum formation in mice. | Harima, R., et al. 2025. Sci Rep. 15: 2413. PMID: 39827215
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR78 Antibody (E-7) | sc-390633 | 200 µg/ml | $322.00 | |||
WDR78 Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-540824 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR78 Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-542395 | 200 µg Ab; 20 µg BP | $361.00 | |||
WDR78 (E-7) Neutralizing Peptide | sc-390633 P | 100 µg/0.5 ml | $69.00 |