USP13 Antibody (E-11): sc-514442

USP13 Antibody (E-11) is a mouse monoclonal IgG2a antibody that detects USP13 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). USP13, also known as ubiquitin specific peptidase 13 or ISOT3, is an 863 amino acid protein that plays a crucial role in the ubiquitin-proteasome system, which is essential for maintaining cellular homeostasis by regulating protein degradation and turnover. USP13 is primarily located in the cytoplasm and nucleus, where USP13 is involved in the deubiquitination process, thereby influencing various cellular functions such as signal transduction, transcriptional regulation, and cell cycle progression. USP13′s ability to remove ubiquitin from target proteins is vital for controlling protein stability and activity, making USP13 a key player in numerous physiological and pathological processes, including cancer progression and neurodegenerative diseases. With specific reactivity and versatile applications, anti-USP13 antibody (E-11) is an invaluable tool for researchers studying the intricate mechanisms of ubiquitin signaling and its implications in health and disease.

The preferred USP13 antibody is USP13 Antibody (B-9): sc-514416.