USP13 Antibody (B-9): sc-514416
- USP13 Antibody (B-9) is a mouse monoclonal IgG2b κ USP13 antibody, cited in 12 publications, provided at 200 µg/ml
- raised against amino acids 71-195 mapping near the N-terminus of USP13 of human origin
- USP13 Antibody (B-9) is recommended for detection of USP13 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-USP13 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for USP13 Antibody (B-9) for WB applications. These reagents are now offered in bundles with USP13 Antibody (B-9) (see ordering information below).
USP13 Antibody (B-9) is a mouse monoclonal IgG2b kappa light chain antibody that detects USP13 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). USP13 Antibody (B-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. USP13, also known as ubiquitin specific peptidase 13 or ISOT3, is a crucial component of the ubiquitin-proteasome system, which regulates protein degradation and various cellular processes. With a length of 863 amino acids, USP13 belongs to the peptidase C19 family and features one UBP-type zinc finger and two UBA domains, which are essential for recognizing and processing ubiquitin. USP13 is highly expressed in testicular and ovarian tissues, where USP13 plays a vital role in catalyzing the hydrolysis of ubiquitin C-terminal thioesters, thereby releasing free ubiquitin and regulating the turnover of proteins involved in critical cellular functions such as signal transduction and cell cycle progression. USP13′s ability to modulate the ubiquitin pathway underscores USP13′s importance in maintaining cellular homeostasis and responding to stress, making USP13 a significant target for research in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
USP13 Antibody (B-9) References:
- A genomic perspective on human proteases. | Southan, C. 2001. FEBS Lett. 498: 214-8. PMID: 11412860
- Human and mouse proteases: a comparative genomic approach. | Puente, XS., et al. 2003. Nat Rev Genet. 4: 544-58. PMID: 12838346
- Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases. | Quesada, V., et al. 2004. Biochem Biophys Res Commun. 314: 54-62. PMID: 14715245
- Screen for ISG15-crossreactive deubiquitinases. | Catic, A., et al. 2007. PLoS One. 2: e679. PMID: 17653289
- Deubiquitinating enzymes: a new class of biological regulators. | D'Andrea, A. and Pellman, D. 1998. Crit Rev Biochem Mol Biol. 33: 337-52. PMID: 9827704
- The genomic organization of Isopeptidase T-3 (ISOT-3), a new member of the ubiquitin specific protease family (UBP). | Timms, KM., et al. 1998. Gene. 217: 101-6. PMID: 9841226
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
USP13 Antibody (B-9) | sc-514416 | 200 µg/ml | $316.00 | |||
USP13 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-526368 | 200 µg Ab; 10 µg BP | $354.00 | |||
USP13 Antibody (B-9): m-IgG2b BP-HRP Bundle | sc-549718 | 200 µg Ab; 10 µg BP | $354.00 | |||
USP13 Antibody (B-9) AC | sc-514416 AC | 500 µg/ml, 25% agarose | $416.00 | |||
USP13 Antibody (B-9) HRP | sc-514416 HRP | 200 µg/ml | $316.00 | |||
USP13 Antibody (B-9) FITC | sc-514416 FITC | 200 µg/ml | $330.00 | |||
USP13 Antibody (B-9) PE | sc-514416 PE | 200 µg/ml | $343.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 488 | sc-514416 AF488 | 200 µg/ml | $357.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 546 | sc-514416 AF546 | 200 µg/ml | $357.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 594 | sc-514416 AF594 | 200 µg/ml | $357.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 647 | sc-514416 AF647 | 200 µg/ml | $357.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 680 | sc-514416 AF680 | 200 µg/ml | $357.00 | |||
USP13 Antibody (B-9) Alexa Fluor® 790 | sc-514416 AF790 | 200 µg/ml | $357.00 |