Date published: 2026-1-11

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USP18 Antibodies

Santa Cruz Biotechnology provides a broad selection of USP18 monoclonal antibodies for research focused on understanding USP18 protein functions. USP18 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). USP18, or Ubiquitin Specific Peptidase 18, plays a crucial role in regulating immune responses and modulating interferon signaling pathways. The deubiquitination function of USP18 is essential in cellular processes such as inflammation and viral defense, making USP18 a significant focus in immunology and disease mechanism research. Understanding USP18 activity can lead to new therapeutic strategies for various conditions, including autoimmune diseases and cancer. Research involving USP18 continues to reveal new insights into cellular regulation and disease progression. Investigating USP18's interaction with other proteins helps uncover complex biological pathways and potential therapeutic targets. Recent studies have highlighted USP18's importance in maintaining cellular homeostasis and its potential as a therapeutic target. Santa Cruz Biotechnology monoclonal antibodies support cutting-edge research that advances our understanding of USP18's role in health and disease.

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USP18 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

USP18 Antibody (E-5)

sc-374064mouse IgG1 κ73-372 (h)WB, IP, IF, ELISAh
5
(3)

USP18 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

USP18 CRISPR/Cas9 KO Plasmid (h)

sc-402259hGene KnockoutGFP
2
(0)

USP18 HDR Plasmid (h)

sc-402259-HDRhHomology Directed RepairPuromycin
2
(0)

USP18 Double Nickase Plasmid (h)

sc-402259-NIChGene KnockoutPuromycin
2
(0)

USP18 Double Nickase Plasmid (h2)

sc-402259-NIC-2hGene KnockoutPuromycin
2
(0)

USP18 CRISPR/Cas9 KO Plasmid (m)

sc-423988mGene KnockoutGFP0
(0)

USP18 HDR Plasmid (m)

sc-423988-HDRmHomology Directed RepairPuromycin0
(0)

USP18 Double Nickase Plasmid (m)

sc-423988-NICmGene KnockoutPuromycin0
(0)

USP18 Double Nickase Plasmid (m2)

sc-423988-NIC-2mGene KnockoutPuromycin0
(0)

USP18 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

USP18 CRISPR Activation Plasmid (h)

sc-402259-ACThGene ActivationPuro, Blast, Hygro
2
(0)

USP18 CRISPR Activation Plasmid (h2)

sc-402259-ACT-2hGene ActivationPuro, Blast, Hygro
2
(0)

USP18 Lentiviral Activation Particles (h)

sc-402259-LAChGene ActivationPuro, Blast, Hygro
2
(0)

USP18 Lentiviral Activation Particles (h2)

sc-402259-LAC-2hGene ActivationPuro, Blast, Hygro
2
(0)

USP18 CRISPR Activation Plasmid (m)

sc-423988-ACTmGene ActivationPuro, Blast, Hygro0
(0)

USP18 CRISPR Activation Plasmid (m2)

sc-423988-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

USP18 Lentiviral Activation Particles (m)

sc-423988-LACmGene ActivationPuro, Blast, Hygro0
(0)

USP18 Lentiviral Activation Particles (m2)

sc-423988-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

USP18 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

USP18 siRNA (h)

sc-60865hGene SilencingN/A
2
(0)

USP18 shRNA Plasmid (h)

sc-60865-SHhGene SilencingPuromycin
2
(0)

USP18 shRNA (h) Lentiviral Particles

sc-60865-VhGene SilencingPuromycin
2
(0)

USP18 siRNA (m)

sc-60866mGene SilencingN/A
1
(0)

USP18 shRNA Plasmid (m)

sc-60866-SHmGene SilencingPuromycin
1
(0)

USP18 shRNA (m) Lentiviral Particles

sc-60866-VmGene SilencingPuromycin
1
(0)