UBQLN3 Antibody (G-9): sc-376548
- UBQLN3 Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 305-496 mapping within an internal region of UBQLN3 of human origin
- Anti-UBQLN3 Antibody (G-9) is recommended for detection of UBQLN3 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-UBQLN3 Antibody (G-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for UBQLN3 Antibody (G-9) for WB applications. These reagents are now offered in bundles with UBQLN3 Antibody (G-9) (see ordering information below).
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UBQLN3 Antibody (G-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects UBQLN3 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-UBQLN3 antibody (G-9) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. UBQLN3, also known as Ubiquilin-3, is a 654 amino acid protein characterized by an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain, which play crucial roles in protein degradation and cellular regulation. UBQLN3 is primarily expressed in the testis, where UBQLN3 interacts with testis-specific cyclin A1 and cyclin A to regulate the cell cycle during spermatogenesis, highlighting its importance in reproductive biology. UBQLN3 belongs to a family of proteins that includes PLIC-1 (Ubiquilin-1), which also contributes to cell cycle regulation, underscoring the significance of ubiquitin-like proteins in maintaining cellular homeostasis and function.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
UBQLN3 Antibody (G-9) References:
- Molecular cloning, chromosome mapping and characterization of UBQLN3 a testis-specific gene that contains an ubiquitin-like domain. | Conklin, D., et al. 2000. Gene. 249: 91-8. PMID: 10831842
- Comparative structural and functional analysis of the olfactory receptor genes flanking the human and mouse beta-globin gene clusters. | Bulger, M., et al. 2000. Proc Natl Acad Sci U S A. 97: 14560-5. PMID: 11121057
- The ubiquitin-proteasome proteolytic pathway: destruction for the sake of construction. | Glickman, MH. and Ciechanover, A. 2002. Physiol Rev. 82: 373-428. PMID: 11917093
- Molecular features of human ubiquitin-like SUMO genes and their encoded proteins. | Su, HL. and Li, SS. 2002. Gene. 296: 65-73. PMID: 12383504
- Association study of the Ubiquilin gene with Alzheimer's disease. | Bensemain, F., et al. 2006. Neurobiol Dis. 22: 691-3. PMID: 16504527
- Analysis of UBQLN1 variants in a Polish Alzheimer's disease patient: control series. | Golan, MP., et al. 2008. Dement Geriatr Cogn Disord. 25: 366-71. PMID: 18340109
- Ubqln3, a testis-specific gene, is dispensable for embryonic development and spermatogenesis in mice. | Yuan, S., et al. 2015. Mol Reprod Dev. 82: 266-7. PMID: 25776854
- MicroRNA-targeting in spermatogenesis: Over-expressions of microRNA-23a/b-3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of patients with oligoasthenozoospermia. | Abu-Halima, M., et al. 2021. Andrology. 9: 1137-1144. PMID: 33784796
- HYPK coordinates degradation of polyneddylated proteins by autophagy. | Ghosh, DK. and Ranjan, A. 2022. Autophagy. 18: 1763-1784. PMID: 34836490
- Chromosome 17 translocation affects sperm morphology: Two case studies and literature review. | Huang, S., et al. 2022. Andrologia. 54: e14620. PMID: 36270636
- UBQLN Family Members Regulate MYC in Lung Adenocarcinoma Cells. | Shah, PP. and Beverly, LJ. 2023. Cancers (Basel). 15: PMID: 37444499
- Identification of hub genes associated with spermatogenesis by bioinformatics analysis. | Liu, S., et al. 2023. Sci Rep. 13: 18435. PMID: 37891374
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
UBQLN3 Antibody (G-9) | sc-376548 | 200 µg/ml | $322.00 | |||
UBQLN3 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-529904 | 200 µg Ab; 10 µg BP | $361.00 | |||
UBQLN3 Antibody (G-9): m-IgGκ BP-HRP Bundle | sc-523003 | 200 µg Ab, 40 µg BP | $361.00 | |||
UBQLN3 Antibody (G-9) AC | sc-376548 AC | 500 µg/ml, 25% agarose | $424.00 | |||
UBQLN3 Antibody (G-9) HRP | sc-376548 HRP | 200 µg/ml | $322.00 | |||
UBQLN3 Antibody (G-9) FITC | sc-376548 FITC | 200 µg/ml | $336.00 | |||
UBQLN3 Antibody (G-9) PE | sc-376548 PE | 200 µg/ml | $349.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 488 | sc-376548 AF488 | 200 µg/ml | $364.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 546 | sc-376548 AF546 | 200 µg/ml | $364.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 594 | sc-376548 AF594 | 200 µg/ml | $364.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 647 | sc-376548 AF647 | 200 µg/ml | $364.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 680 | sc-376548 AF680 | 200 µg/ml | $364.00 | |||
UBQLN3 Antibody (G-9) Alexa Fluor® 790 | sc-376548 AF790 | 200 µg/ml | $364.00 |