Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TTI1 (TELO2-interacting protein 1 homolog), also known as SMG10, is a 1,089 amino acid protein that is widely expressed and belongs to the TTI1 family. TTI1 functions as a regulator of the DNA damage response (DDR) and is a component of the TTT complex, which is necessary for the stabilization of protein levels of the phosphatidylinositol 3-kinase (PIKK) family. The TTT complex is a part of the cellular resistance to DNA damage stresses such as ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). In combination with the TTT complex and HSP90, TTI1 may play a role in the proper folding of newly synthesized PIKKs. TTI1 also is involved in the assembly of mTORC1 and mTORC2 complexes, as well as their stabilization and maintenance. TTI1 is post-tanslationally modified at serine 459 and the gene encoding this protein maps to human chromosome 20.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.