TRβ1 Antibody (A-7): sc-398007
- TRβ1 Antibody (A-7) is a mouse monoclonal IgG1 κ, cited in 4 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 2-27 at the N-terminus of TRβ1 of human origin
- Anti-TR beta 1 Antibody (A-7) is recommended for detection of TRβ1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-TR beta 1 Antibody (A-7) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for ChIP application (sc-398007 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TRβ1 Antibody (A-7) for WB applications. These reagents are now offered in bundles with TRβ1 Antibody (A-7) (see ordering information below).
QUICK LINKS
TRβ1 (A-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects TRβ1 of mouse, rat and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF) and enzyme-linked immunosorbent assay (ELISA). TRβ1 (A-7) antibody is available as non-conjugated form, as well as multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC) and multiple Alexa Fluor® conjugates. Thyroid hormone nuclear receptors (TRs) are ligand-dependent transcription factors which regulate growth, differentiation and development, and represent members of the steroid/retinoic acid superfamily. TRα and TRβ genes have been mapped to human chromosomes 17 and 3, respectively. TRs bind to thyroid hormone response elements (TREs) with half-site binding motifs in palindromes, direct repeats or inverted palindromes orientations. Binding affinities vary and are influenced by 3,5,3′-triiodo-L-thyronine (T3). TR nuclear accessory proteins, particularly retinoid X receptors (RXRα, RXRβ and RXRγ), modulate transcriptional regulation through heterodimerization with TRs. TRβ1 forms a complex with PI 3-kinase p85α subunit and plays an important role in T3-induced activation of Akt in pancreatic β cells.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TRβ1 Antibody (A-7) | sc-398007 | 200 µg/ml | $322.00 | |||
TRβ1 Antibody (A-7): m-IgG Fc BP-HRP Bundle | sc-530658 | 200 µg Ab; 10 µg BP | $361.00 | |||
TRβ1 Antibody (A-7): m-IgGκ BP-HRP Bundle | sc-524178 | 200 µg Ab, 40 µg BP | $361.00 | |||
TRβ1 Antibody (A-7): m-IgG1 BP-HRP Bundle | sc-544186 | 200 µg Ab; 20 µg BP | $361.00 | |||
TRβ1 Antibody (A-7) X | sc-398007 X | 200 µg/0.1 ml | $322.00 | |||
TRβ1 Antibody (A-7) AC | sc-398007 AC | 500 µg/ml, 25% agarose | $424.00 | |||
TRβ1 Antibody (A-7) HRP | sc-398007 HRP | 200 µg/ml | $322.00 | |||
TRβ1 Antibody (A-7) FITC | sc-398007 FITC | 200 µg/ml | $336.00 | |||
TRβ1 Antibody (A-7) PE | sc-398007 PE | 200 µg/ml | $349.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 488 | sc-398007 AF488 | 200 µg/ml | $364.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 546 | sc-398007 AF546 | 200 µg/ml | $364.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 594 | sc-398007 AF594 | 200 µg/ml | $364.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 647 | sc-398007 AF647 | 200 µg/ml | $364.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 680 | sc-398007 AF680 | 200 µg/ml | $364.00 | |||
TRβ1 Antibody (A-7) Alexa Fluor® 790 | sc-398007 AF790 | 200 µg/ml | $364.00 | |||
TRβ1 (A-7) Neutralizing Peptide | sc-398007 P | 100 µg/0.5 ml | $69.00 |