TORC1 Antibody (B-12): sc-390881
- TORC1 Antibody (B-12) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 613-624 near the C-terminus of TORC1 of human origin
- recommended for detection of TORC1 of mouse, rat, human and avian origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine, porcine and avian
- TransCruz reagent for ChIP application (sc-390881 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TORC1 Antibody (B-12) for WB applications. These reagents are now offered in bundles with TORC1 Antibody (B-12) (see ordering information below).
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TORC1 Antibody (B-12) is a mouse monoclonal IgG2b antibody that detects TORC1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TORC1, or transducer of regulated cAMP response element-binding protein 1, plays a crucial role in the regulation of gene expression by acting as a coactivator for the cAMP response element-binding protein (CREB). TORC1 is primarily located in the nucleus, where TORC1 is involved in the transcriptional activation of genes in response to hormonal signals, particularly those mediated by cAMP. Nuclear localization of TORC1 is vital for function, as this allows for direct interaction with CREB and other transcription factors, facilitating the expression of genes essential for processes such as metabolism, cell growth, and differentiation. TORC1 undergoes phosphorylation, which modulates activity and stability, further emphasizing the importance of regulatory mechanisms in cellular signaling pathways. Anti-TORC1 antibody (B-12) is an invaluable tool for researchers studying these critical pathways and their implications in various physiological and pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TORC1 Antibody (B-12) | sc-390881 | 200 µg/ml | $322.00 | |||
TORC1 Antibody (B-12): m-IgG Fc BP-HRP Bundle | sc-538107 | 200 µg Ab; 10 µg BP | $361.00 | |||
TORC1 Antibody (B-12): m-IgGκ BP-HRP Bundle | sc-535658 | 200 µg Ab; 40 µg BP | $361.00 | |||
TORC1 Antibody (B-12): m-IgG2b BP-HRP Bundle | sc-549919 | 200 µg Ab; 10 µg BP | $361.00 | |||
TORC1 (B-12) Neutralizing Peptide | sc-390881 P | 100 µg/0.5 ml | $69.00 | |||
TORC1 Antibody (B-12) X | sc-390881 X | 200 µg/0.1 ml | $322.00 |