TIA-1 Antibody (C-10): sc-166246
- TIA-1 Antibody (C-10) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 37-65 near the N-terminus of TIA-1 of human origin
- recommended for detection of TIA-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See TIA-1 (G-3): sc-166247 for TIA-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TIA-1 Antibody (C-10) for WB and IHC(P) applications. These reagents are now offered in bundles with TIA-1 Antibody (C-10) (see ordering information below).
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TIA-1 Antibody (C-10) is a mouse monoclonal IgG1 antibody that detects TIA-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). TIA-1, a crucial type I transmembrane protein, is primarily located in the nucleus and plays a significant role in the regulation of apoptosis, particularly in viral immunity. TIA-1 helps mediate programmed cell death, which is essential for maintaining cellular homeostasis and eliminating infected or damaged cells. Upon FAS ligation, TIA-1 rapidly translocates to the cytoplasm, where TIA-1 participates in the apoptotic signaling cascade, leading to DNA fragmentation. This translocation is a critical step in the apoptotic process, highlighting TIA-1′s importance in cellular responses to stress and infection. Additionally, TIA-1 interacts with other proteins involved in apoptosis, such as TIAR, which further underscores TIA-1′s role in the complex network of cellular signaling pathways. Anti-TIA-1 antibody (C-10) serves as an invaluable tool for researchers studying apoptosis and immune responses, providing insights into cell death mechanisms and potential therapeutic targets for diseases characterized by dysregulated apoptosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TIA-1 Antibody (C-10) | sc-166246 | 200 µg/ml | $322.00 | |||
TIA-1 Antibody (C-10): m-IgG Fc BP-HRP Bundle | sc-537464 | 200 µg Ab; 10 µg BP | $361.00 | |||
TIA-1 Antibody (C-10): m-IgGκ BP-HRP Bundle | sc-534738 | 200 µg Ab; 40 µg BP | $361.00 | |||
TIA-1 Antibody (C-10): m-IgG1 BP-HRP Bundle | sc-545195 | 200 µg Ab; 20 µg BP | $361.00 | |||
TIA-1 (C-10) Neutralizing Peptide | sc-166246 P | 100 µg/0.5 ml | $69.00 |