Anti-TBC1D10C Antibody (C-8) is a mouse monoclonal IgG2a (kappa light chain) TBC1D10C antibody provided at 200 µg/ml
raised against amino acids 26-138 mapping near the N-terminus of TBC1D10C of human origin
Anti-TBC1D10C Antibody (C-8) is recommended for detection of TBC1D10C of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
Anti-TBC1D10C Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of TBC1D10C (C-8): sc-393642.
m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TBC1D10C Antibody (C-8) for WB and IHC(P) applications. These reagents are now offered in bundles with TBC1D10C Antibody (C-8) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
TBC1D10C Antibody (C-8) is a high quality monoclonal TBC1D10C antibody (also designated TBC1D10C antibody) suitable for the detection of the TBC1D10C protein of mouse, rat and human origin. TBC1D10C Antibody (C-8) is available as both the non-conjugated anti-TBC1D10C antibody form, as well as multiple conjugated forms of anti-TBC1D10C antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. TBC1D10C (TBC1 domain family, member 10C), also known as Carabin, is a 446 amino acid protein that contains one Rab-GAP TBC domain. Expressed at high levels in spleen and peripheral blood leukocytes, TBC1D10C functions as a Ras GTPase-activating protein that interacts with and acts as a negative feedback inhibitor of PP2B proteins, thereby mediating crosstalk between Ras and PP2Bs. The gene encoding TBC1D10C maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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