TAPP2 Antibody (C-8): sc-271307
- TAPP2 Antibody (C-8) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping at the C-terminus of TAPP2 of human origin
- recommended for detection of TAPP2 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for TAPP2 Antibody (C-8) for WB applications. These reagents are now offered in bundles with TAPP2 Antibody (C-8) (see ordering information below).
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TAPP2 Antibody (C-8) is a mouse monoclonal IgG2b antibody that detects TAPP2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). TAPP2, or tandem PH domain-containing protein 2, is a crucial cytoplasmic adaptor protein that plays a significant role in cellular signaling pathways, particularly in the immune response. TAPP2 is predominantly expressed in heart and kidney tissues, where TAPP2 is involved in the recruitment of signaling molecules to the plasma membrane upon growth factor stimulation. This recruitment is facilitated by the specific interaction of TAPP2′s C-terminal pleckstrin homology domain with phosphatidylinositol 3,4-bisphosphate, which is essential for the formation of membrane ruffles rich in F-Actin. TAPP2′s importance extends to a regulatory role in enhancing NFAT-dependent transcriptional activation following B cell receptor engagement, thereby influencing the activation and function of both B and T cells. Anti-TAPP2 antibody (C-8) enables researchers to gain valuable insights into the mechanisms of immune cell activation and the broader implications of TAPP2 in various physiological and pathological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
TAPP2 Antibody (C-8) | sc-271307 | 200 µg/ml | $316.00 | |||
TAPP2 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-537607 | 200 µg Ab; 10 µg BP | $354.00 | |||
TAPP2 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-534922 | 200 µg Ab; 40 µg BP | $354.00 | |||
TAPP2 Antibody (C-8): m-IgG2b BP-HRP Bundle | sc-549892 | 200 µg Ab; 10 µg BP | $354.00 | |||
TAPP2 (C-8) Neutralizing Peptide | sc-271307 P | 100 µg/0.5 ml | $68.00 |