SMYD1 Antibody (D-1): sc-514805
- SMYD1 Antibody (D-1) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 181-480 mapping near the C-terminus of SMYD1 of human origin
- SMYD1 Antibody (D-1) is recommended for detection of SMYD1 of human origin by WB, IP, IF and ELISA
- Anti-SMYD1 Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SMYD1 Antibody (D-1) for WB applications. These reagents are now offered in bundles with SMYD1 Antibody (D-1) (see ordering information below).
QUICK LINKS
SMYD1 Antibody (D-1) is a mouse monoclonal IgG2a kappa light chain antibody that detects SMYD1 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SMYD1 Antibody (D-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SMYD1, also known as SET and MYND domain-containing protein 1, BOP, ZMYND18, or ZMYND22, functions as a critical nuclear and cytoplasmic protein with a vital role in cardiac morphogenesis and cardiomyocyte differentiation. SMYD1 contains one SET domain and one MYND-type zinc finger, essential for functioning as a transcription factor. SMYD1 is specifically expressed in cardiac and skeletal muscle, where SMYD1 interacts with histone deacetylases such as HDAC1, HDAC2, and HDAC3, functioning as a histone deacetylase-dependent transcriptional repressor. Defects or deletions in the gene encoding SMYD1 can lead to impaired maturation of ventricular cardiomyocytes, highlighting SMYD1′s crucial involvement in normal cardiac development and potential implications for heart disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SMYD1 Antibody (D-1) | sc-514805 | 200 µg/ml | $322.00 | |||
SMYD1 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-531222 | 200 µg Ab; 10 µg BP | $361.00 | |||
SMYD1 Antibody (D-1): m-IgGκ BP-HRP Bundle | sc-524848 | 200 µg Ab, 40 µg BP | $361.00 | |||
SMYD1 Antibody (D-1): m-IgG2a BP-HRP Bundle | sc-547732 | 200 µg Ab; 10 µg BP | $361.00 | |||
SMYD1 Antibody (D-1) AC | sc-514805 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SMYD1 Antibody (D-1) HRP | sc-514805 HRP | 200 µg/ml | $322.00 | |||
SMYD1 Antibody (D-1) FITC | sc-514805 FITC | 200 µg/ml | $336.00 | |||
SMYD1 Antibody (D-1) PE | sc-514805 PE | 200 µg/ml | $349.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 488 | sc-514805 AF488 | 200 µg/ml | $364.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 546 | sc-514805 AF546 | 200 µg/ml | $364.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 594 | sc-514805 AF594 | 200 µg/ml | $364.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 647 | sc-514805 AF647 | 200 µg/ml | $364.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 680 | sc-514805 AF680 | 200 µg/ml | $364.00 | |||
SMYD1 Antibody (D-1) Alexa Fluor® 790 | sc-514805 AF790 | 200 µg/ml | $364.00 |