Smad4 Antibody (DCS-46): sc-73599
- Smad4 Antibody (DCS-46) is a mouse monoclonal IgG1 κ, cited in 2 publications, provided at 200 µg/ml
- raised against recombinant Smad4 of human origin
- recommended for detection of Smad4 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See Smad4 (B-8): sc-7966 for Smad4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Smad4 Antibody (DCS-46) for WB and IHC(P) applications. These reagents are now offered in bundles with Smad4 Antibody (DCS-46) (see ordering information below).
Smad4 Antibody (DCS-46) is a mouse monoclonal IgG1 antibody that detects Smad4 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Smad4, also known as DPC4, plays a crucial role in the transforming growth factor-beta (TGF-β) and bone morphogenetic protein (BMP) signaling pathways, acting as a central mediator that integrates signals from various Smad family members. anti-Smad4 antibody (DCS-46) recognizes nuclear-localized Smad4, where Smad4 forms complexes with other Smad proteins to regulate gene expression in response to extracellular signals. Nuclear localization of Smad4 enables direct influence on transcriptional programs controlling cellular processes such as proliferation, differentiation, and apoptosis. Dysregulation of Smad4 has been implicated in various diseases, including cancer, making Smad4 an important target for research. Smad4 monoclonal antibody (DCS-46) serves as an essential tool for studying the dynamics of TGF-β/BMP signaling and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Smad4 Antibody (DCS-46) | sc-73599 | 200 µg/ml | $322.00 | |||
Smad4 Antibody (DCS-46): m-IgG Fc BP-HRP Bundle | sc-537225 | 200 µg Ab; 10 µg BP | $361.00 | |||
Smad4 Antibody (DCS-46): m-IgGκ BP-HRP Bundle | sc-534438 | 200 µg Ab; 40 µg BP | $361.00 | |||
Smad4 Antibody (DCS-46): m-IgG1 BP-HRP Bundle | sc-545090 | 200 µg Ab; 20 µg BP | $361.00 |