SIRP-β1 Antibody (B4B6): sc-21800
- SIRP-β1 Antibody (B4B6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against a recombinant extracellular domain of human SIRP-β
- recommended for detection of SIRP-β1 of human origin by IP and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for SIRP-β1 Antibody (B4B6). These reagents are now offered in bundles with SIRP-β1 Antibody (B4B6) (see ordering information below).
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SIRP-β1 Antibody (B4B6) is a mouse monoclonal IgG1 antibody that detects SIRP-β1 in human samples through immunoprecipitation (IP) and flow cytometry (FCM) applications. SIRP-β1 is a member of the signal-regulatory protein family, which plays a crucial role in modulating immune responses. Unlike SIRP-α1, SIRP-β1 lacks a cytoplasmic domain, which means SIRP-β1 does not participate in the same signaling pathways, yet shares extensive sequence homology in its extracellular region. This unique structure allows SIRP-β1 to interact with various ligands, including CD47, which is essential for mediating inhibitory signals in immune cells. The interaction between SIRP-β1 and CD47 is particularly important as SIRP-β1 helps to regulate the phagocytic activity of macrophages, thereby influencing immune tolerance and the response to tumors. Using anti-SIRP-β1 antibody (B4B6) in research can provide insights into the mechanisms of immune regulation and potential therapeutic targets for enhancing anti-tumor immunity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SIRP-β1 Antibody (B4B6) | sc-21800 | 200 µg/ml | $316.00 | |||
SIRP-β1 Antibody (B4B6): m-IgG Fc BP-HRP Bundle | sc-536678 | 200 µg Ab; 10 µg BP | $354.00 | |||
SIRP-β1 Antibody (B4B6): m-IgGκ BP-HRP Bundle | sc-533837 | 200 µg Ab; 40 µg BP | $354.00 | |||
SIRP-β1 Antibody (B4B6): m-IgG1 BP-HRP Bundle | sc-544759 | 200 µg Ab; 20 µg BP | $354.00 | |||
SIRP-β Antibody (B4B6) FITC | sc-21800 FITC | 200 µg/ml | $330.00 | |||
SIRP-β1 Antibody (B4B6) PE | sc-21800 PE | 200 µg/ml | $343.00 |