SERCA2 Antibody (IID8): sc-53010
- SERCA2 Antibody (IID8) is a mouse monoclonal IgG1 κ, cited in 24 publications, provided at 200 µg/ml
- raised against purified canine cardiac sarcoplasmic reticulum
- Anti-SERCA2 Antibody (IID8) is recommended for detection of SERCA2 of mouse, rat and human origin by WB, IP, IF and IHC(P); also reactive with additional species, including and rabbit, bovine, canine and porcine
- Anti-SERCA2 Antibody (IID8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for SERCA2 Antibody (IID8) for WB and IHC(P) applications. These reagents are now offered in bundles with SERCA2 Antibody (IID8) (see ordering information below).
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SERCA2 Antibody (IID8) is a mouse monoclonal IgG1 kappa light chain antibody that detects SERCA2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-SERCA2 antibody (IID8) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. SERCA2 plays a crucial role in calcium homeostasis by mediating calcium ion uptake into the sarcoplasmic reticulum, which is essential for muscle contraction and relaxation. This process maintains low cytoplasmic calcium concentrations, preventing excessive muscle contraction and ensuring proper cardiac function. SERCA2 undergoes tissue-specific processing, resulting in two isoforms: SERCA2a, predominantly found in type I (slow) skeletal, cardiac, and smooth muscle, and SERCA2b, expressed in various cell types. Calcium level regulation by SERCA2 particularly influences cardiac muscle contractility and relaxation, highlighting significance in cardiovascular health. SERCA2 (IID8) monoclonal antibody serves as an invaluable tool for researchers studying calcium signaling and muscle physiology, providing insights into molecular mechanisms underlying muscle function and related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
SERCA2 Antibody (IID8) | sc-53010 | 200 µg/ml | $322.00 | |||
SERCA2 Antibody (IID8): m-IgG Fc BP-HRP Bundle | sc-526758 | 200 µg Ab; 10 µg BP | $361.00 | |||
SERCA2 Antibody (IID8): m-IgG1 BP-HRP Bundle | sc-532131 | 200 µg Ab; 20 µg BP | $361.00 | |||
SERCA2 Antibody (IID8) AC | sc-53010 AC | 500 µg/ml, 25% agarose | $424.00 | |||
SERCA2 Antibody (IID8) HRP | sc-53010 HRP | 200 µg/ml | $322.00 | |||
SERCA2 Antibody (IID8) FITC | sc-53010 FITC | 200 µg/ml | $336.00 | |||
SERCA2 Antibody (IID8) PE | sc-53010 PE | 200 µg/ml | $349.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 488 | sc-53010 AF488 | 200 µg/ml | $364.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 546 | sc-53010 AF546 | 200 µg/ml | $364.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 594 | sc-53010 AF594 | 200 µg/ml | $364.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 647 | sc-53010 AF647 | 200 µg/ml | $364.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 680 | sc-53010 AF680 | 200 µg/ml | $364.00 | |||
SERCA2 Antibody (IID8) Alexa Fluor® 790 | sc-53010 AF790 | 200 µg/ml | $364.00 |