SCNM1 Antibody (F-9): sc-376457

SCNM1 Antibody (F-9) is a mouse monoclonal IgG2a antibody that detects SCNM1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). SCNM1, or sodium channel modifier 1, is a 230 amino acid protein characterized by a single matrin-type zinc finger domain, which plays a crucial role in RNA splicing and regulation of sodium channel-related proteins. SCNM1′s localization in the nucleus enables interaction with pre-mRNA and influences splicing processes, affecting expression of various sodium channels vital for maintaining cellular excitability and signaling. SCNM1 exists in two alternatively spliced isoforms, adding complexity to regulatory functions. SCNM1′s gene is located on chromosome 1, the largest human chromosome, associated with several genetic disorders, including Stickler syndrome and Parkinson′s disease, highlighting SCNM1′s importance in both normal physiology and disease states. Anti-SCNM1 antibody (F-9) serves as an essential tool for researchers investigating SCNM1′s role in cellular processes and implications in various health conditions.

The preferred SCNM1 antibody is SCNM1 Antibody (A-6): sc-376328.