RCC1 Antibody (H-5): sc-376715
- RCC1 Antibody (H-5) is a mouse monoclonal IgG3 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-27 at the N-terminus of RCC1 of human origin
- recommended for detection of RCC1 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG3 BP-HRP is the preferred secondary detection reagent for RCC1 Antibody (H-5) for WB applications. This reagent is now offered in a bundle with RCC1 Antibody (H-5) (see ordering information below).
QUICK LINKS
SEE ALSO...
RCC1 Antibody (H-5) is a mouse monoclonal IgG3 antibody that detects RCC1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RCC1, or regulator of chromosome condensation 1, plays a crucial role in the regulation of the small Ras-related protein Ran, which is essential for various cellular processes, including DNA replication and the transport of RNA and proteins through the nuclear pore complex. The function of RCC1 as a guanine nucleotide exchange factor is vital, as RCC1 facilitates the conversion of inactive Ran GDP to its active form, Ran GTP, thereby influencing the dynamics of nuclear transport and cell cycle progression. This regulation is particularly important during mitosis, where proper localization and activity of Ran are necessary for chromosomal stability and successful completion of cell division. By modulating Ran GTP levels, RCC1 ensures cellular processes are executed efficiently, highlighting RCC1′s significance in maintaining cellular homeostasis and function. Anti-RCC1 antibody (H-5) is an invaluable tool for researchers studying these critical pathways and their implications in cellular biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RCC1 Antibody (H-5) | sc-376715 | 200 µg/ml | $322.00 | |||
RCC1 Antibody (H-5): m-IgG3 BP-HRP Bundle | sc-550460 | 200 µg Ab; 40 µg BP | $361.00 | |||
RCC1 (H-5) Neutralizing Peptide | sc-376715 P | 100 µg/0.5 ml | $69.00 |