RBM12 Antibody (E-6): sc-514259

RBM12 Antibody (E-6) is a mouse monoclonal IgG2a antibody that detects RBM12 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RBM12, also known as SWAN, HRIHFB2091, or KIAA0765, is a 932 amino acid protein that plays a crucial role in the regulation of alternative splicing and apoptosis modulation, making RBM12 significant in various cellular processes. RBM12 is primarily localized in the nucleus, where RBM12 participates in RNA processing and gene expression regulation. The presence of multiple proline-rich regions, transmembrane domains, and three RNA recognition motifs (RRM) within RBM12′s structure highlights RBM12′s functional versatility and importance in RNA binding. Notably, RBM12 shares a genomic region with copine I (CPNE1) at human chromosome location 20q11.21, indicating a potential functional interaction between these two proteins, which may further influence cellular signaling pathways and gene regulation. Anti-RBM12 antibody (E-6) is an essential tool for researchers investigating the intricate roles of RNA-binding proteins in cellular mechanisms and disease states.

The preferred RBM12 antibody is RBM12 Antibody (B-12): sc-514258.