RAP55 Antibody (G-5): sc-398633

RAP55 Antibody (G-5) is a mouse monoclonal IgG2b antibody that detects RAP55 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). RAP55, also known as LSM14A, is a 463 amino acid protein that plays a crucial role in RNA metabolism and is essential for the formation of processing bodies (P-bodies), which are involved in mRNA decay and storage. RAP55 contains a FFD-TFG box domain and features an Sm-like sequence motif, which is vital for interaction with other Sm-like proteins, forming stable heteromers that are integral to tri-snRNP particles necessary for pre-mRNA splicing. Notably, RAP55 undergoes phosphorylation in response to DNA damage, likely mediated by ATM or ATR kinases, highlighting involvement in cellular stress responses. The RAP55 gene is conserved across a wide range of species, including chimpanzees, dogs, cows, and various model organisms, and is located on human chromosome 19q13.11. With RAP55′s ability to interact with specific proteins involved in RNA processing and significance in cellular mechanisms, anti-RAP55 antibody (G-5) is an invaluable tool for researchers studying gene expression regulation and RNA metabolism.

The preferred RAP55 antibody is RAP55 Antibody (C-5): sc-398552.