RANTES Antibody (VL2): sc-32250
- RANTES Antibody (VL2) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against recombinant human RANTES protein
- recommended for detection of RANTES of human origin by WB, IP and IF
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for RANTES Antibody (VL2) for WB applications. These reagents are now offered in bundles with RANTES Antibody (VL2) (see ordering information below).
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RANTES Antibody (VL2) is a mouse monoclonal IgG2b antibody that detects RANTES in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). RANTES, also known as regulated upon activation, normal T cell expressed and secreted, plays a crucial role in the immune response by acting as a potent chemoattractant for various immune cells, including monocytes and natural killer (NK) cells. RANTES is primarily expressed by platelets, eosinophils, fibroblasts, macrophages, endothelial cells, and T lymphocytes, highlighting RANTES′s importance in mediating inflammatory responses and recruiting immune cells to sites of infection or injury. Notably, RANTES is characterized by a unique structure that includes a set of conserved cysteines, which are essential for stability and function. These cysteines allow RANTES to adopt a specific conformation necessary for binding to receptors, thereby facilitating a role in cell signaling and migration. Anti-RANTES antibody (VL2) serves as an invaluable tool for researchers studying the dynamics of immune cell trafficking and the underlying mechanisms of various inflammatory diseases.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
RANTES Antibody (VL2) References:
- CCL5/RANTES gene polymorphisms in Slavonic patients with myocardial infarction. | Tereshchenko, IP., et al. 2011. Mediators Inflamm. 2011: 525691. PMID: 21547257
- RANTES, MCP-1 chemokines and factors describing rheumatoid arthritis. | Pavkova Goldbergova, M., et al. 2012. Mol Immunol. 52: 273-8. PMID: 22750227
- Increased circulating RANTES in type 2 diabetes. | Dworacka, M., et al. 2014. Eur Cytokine Netw. 25: 46-51. PMID: 25373852
- Haemophilus parasuis infection activates chemokine RANTES in PK-15 cells. | Chen, Y., et al. 2015. Mol Immunol. 67: 661-6. PMID: 26198698
- RANTES correlates with inflammatory activity and synaptic excitability in multiple sclerosis. | Mori, F., et al. 2016. Mult Scler. 22: 1405-1412. PMID: 26733422
- Chemokine RANTES is increased at early stages of coronary artery disease. | Podolec, J., et al. 2016. J Physiol Pharmacol. 67: 321-8. PMID: 27226191
- Bis(monoacylglycero)phosphate inhibits TLR4-dependent RANTES production in macrophages. | Ciesielska, A., et al. 2017. Int J Biochem Cell Biol. 83: 15-26. PMID: 27939812
- RANTES levels as a determinant of falciparum malaria severity or recovery. | Bujarbaruah, D., et al. 2017. Parasite Immunol. 39: PMID: 28686299
- Elevated serum RANTES chemokine levels in autoimmune Addison disease. | Fichna, M., et al. 2018. Pol Arch Intern Med. 128: 216-221. PMID: 29498364
- A Preventive Role of RANTES Genetic Variation against Undifferentiated Schizophrenia. | Saoud, H., et al. 2022. Immunol Invest. 51: 1843-1855. PMID: 35476033
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
RANTES Antibody (VL2) | sc-32250 | 200 µg/ml | $322.00 | |||
RANTES Antibody (VL2): m-IgG Fc BP-HRP Bundle | sc-536722 | 200 µg Ab; 10 µg BP | $361.00 | |||
RANTES Antibody (VL2): m-IgGκ BP-HRP Bundle | sc-533883 | 200 µg Ab; 40 µg BP | $361.00 | |||
RANTES Antibody (VL2): m-IgG2b BP-HRP Bundle | sc-549824 | 200 µg Ab; 10 µg BP | $361.00 |