Rab 3 GAP p150 Antibody (B-9): sc-398315
- Rab 3 GAP p150 Antibody (B-9) is a mouse monoclonal IgG1 κ Rab 3 GAP p150 antibody provided at 200 µg/ml
- raised against amino acids 64-173 mapping near the N-terminus of Rab 3 GAP p150 of human origin
- Rab 3 GAP p150 Antibody (B-9) is recommended for detection of Rab 3 GAP p150 of human origin by WB, IP, IF and ELISA; also reactive with additional species, including equine
- Anti-Rab 3 GAP p150 Antibody (B-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Rab 3 GAP p150 Antibody (B-9) for WB applications. These reagents are now offered in bundles with Rab 3 GAP p150 Antibody (B-9) (see ordering information below).
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Rab 3 GAP p150 Antibody (B-9) is a mouse monoclonal IgG1 kappa light chain antibody that detects Rab 3 GAP p150 of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Rab 3 GAP p150 antibody (B-9) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Rab 3 GAP p150, also known as RAB3GAP2 or Rab3 GTPase-activating protein non-catalytic subunit, is a crucial component of the Rab3 GTPase-activating complex, which plays a significant role in regulating neurotransmitter release by inactivating Rab3 GTPases. This protein is composed of 1,393 amino acids and is widely expressed across various tissues, highlighting its importance in cellular signaling pathways. Mutations in the Rab 3 GAP p150 gene are linked to Martsolf and Warburg Micro syndrome, both of which present with congenital cataracts, microphthalmia, postnatal microcephaly, and developmental delays, inherited in an autosomal recessive manner. The gene encoding Rab 3 GAP p150 is highly conserved across species, including chimpanzees, dogs, cows, rats, chickens, zebrafish, fruit flies, mosquitoes, Arabidopsis thaliana, and rice, and consists of 36 exons, mapping to human chromosome 1q41. The interaction of Rab 3 GAP p150 with DMXL2 further underscores its functional significance in cellular processes, making Rab 3 GAP p150 (B-9) monoclonal antibody an essential tool for researchers studying these pathways.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Rab 3 GAP p150 Antibody (B-9) | sc-398315 | 200 µg/ml | $322.00 | |||
Rab 3 GAP p150 Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-530755 | 200 µg Ab; 10 µg BP | $361.00 | |||
Rab 3 GAP p150 Antibody (B-9): m-IgGκ BP-HRP Bundle | sc-524290 | 200 µg Ab, 40 µg BP | $361.00 | |||
Rab 3 GAP p150 Antibody (B-9): m-IgG1 BP-HRP Bundle | sc-544236 | 200 µg Ab; 20 µg BP | $361.00 | |||
Rab 3 GAP p150 Antibody (B-9) AC | sc-398315 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Rab 3 GAP p150 Antibody (B-9) HRP | sc-398315 HRP | 200 µg/ml | $322.00 | |||
Rab 3 GAP p150 Antibody (B-9) FITC | sc-398315 FITC | 200 µg/ml | $336.00 | |||
Rab 3 GAP p150 Antibody (B-9) PE | sc-398315 PE | 200 µg/ml | $349.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 488 | sc-398315 AF488 | 200 µg/ml | $364.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 546 | sc-398315 AF546 | 200 µg/ml | $364.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 594 | sc-398315 AF594 | 200 µg/ml | $364.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 647 | sc-398315 AF647 | 200 µg/ml | $364.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 680 | sc-398315 AF680 | 200 µg/ml | $364.00 | |||
Rab 3 GAP p150 Antibody (B-9) Alexa Fluor® 790 | sc-398315 AF790 | 200 µg/ml | $364.00 |