PYST2 Antibody (C-9): sc-377381
- PYST2 Antibody (C-9) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against amino acids 57-104 mapping within an internal region of PYST2 of human origin
- recommended for detection of PYST2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PYST2 Antibody (C-9) for WB and IHC(P) applications. These reagents are now offered in bundles with PYST2 Antibody (C-9) (see ordering information below).
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SEE ALSO...
PYST2 Antibody (C-9) is a mouse monoclonal IgG1 antibody that detects PYST2 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). PYST2, a member of the dual specificity phosphatases (DSPs), plays a crucial role in regulating mitogen-activated protein (MAP) kinase signaling pathways by selectively dephosphorylating phosphothreonine and phosphotyrosine residues within MAP kinases. This regulation helps maintain cellular homeostasis and modulates responses to growth factors and cellular stressors. PYST2 expression is induced under various physiological conditions, allowing anti-PYST2 antibody (C-9) to negatively regulate key MAP kinase superfamily members, including MAPK/ERK, SAPK/JNK, and p38, thereby influencing critical cellular processes such as proliferation, differentiation, and apoptosis. Notably, PYST2 has been found to be overexpressed in patients with acute myelogenous leukemia (AML), highlighting PYST2′s potential as a biomarker for this malignancy and underscoring the importance of understanding its function in cancer biology. With robust reactivity and versatility in applications, PYST2 (C-9) monoclonal antibody serves as an essential tool for researchers investigating the intricate signaling networks that govern cellular responses.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PYST2 Antibody (C-9) | sc-377381 | 200 µg/ml | $322.00 | |||
PYST2 Antibody (C-9): m-IgG Fc BP-HRP Bundle | sc-538044 | 200 µg Ab; 10 µg BP | $361.00 | |||
PYST2 Antibody (C-9): m-IgGκ BP-HRP Bundle | sc-535568 | 200 µg Ab; 40 µg BP | $361.00 | |||
PYST2 Antibody (C-9): m-IgG1 BP-HRP Bundle | sc-545498 | 200 µg Ab; 20 µg BP | $361.00 |