PP2A-Aα/β Antibody (B-1): sc-374264
- PP2A-Aα/β Antibody (B-1) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 574-601 at the C-terminus of PP2A-Aα/β of human origin
- recommended for detection of PP2A-Aα and PP2A-Aβ of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and porcine and canine
- See PP2A-Aα (6G3): sc-56954 for PP2A-Aα/β antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for PP2A-Aα/β Antibody (B-1) for WB applications. These reagents are now offered in bundles with PP2A-Aα/β Antibody (B-1) (see ordering information below).
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PP2A-Aα/β Antibody (B-1) is a mouse monoclonal IgG2a antibody that detects PP2A-Aα/β in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). PP2A-Aα/β is a crucial regulatory subunit of the protein phosphatase 2A (PP2A) complex, which plays a vital role in cellular signaling pathways by dephosphorylating serine and threonine residues on target proteins. This dephosphorylation is essential for various cellular functions, including cell division, apoptosis, and maintaining cellular homeostasis. The PP2A complex is composed of a catalytic subunit and regulatory subunits, with PP2A-Aα and PP2A-Aβ being key members that modulate the activity and specificity of the phosphatase. The interaction of PP2A-Aα/β with different regulatory subunits allows for the fine-tuning of signaling pathways, making PP2A-Aα/β a critical player in processes such as tumor suppression and the regulation of cell growth. Given its importance in cellular regulation, anti-PP2A-Aα/β antibody (B-1) is an invaluable tool for researchers studying the intricate mechanisms of signal transduction and the role of phosphatases in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PP2A-Aα/β Antibody (B-1) | sc-374264 | 200 µg/ml | $322.00 | |||
PP2A-Aα/β Antibody (B-1): m-IgG Fc BP-HRP Bundle | sc-537945 | 200 µg Ab; 10 µg BP | $361.00 | |||
PP2A-Aα/β Antibody (B-1): m-IgGκ BP-HRP Bundle | sc-535431 | 200 µg Ab; 40 µg BP | $361.00 | |||
PP2A-Aα/β Antibody (B-1): m-IgG2a BP-HRP Bundle | sc-548155 | 200 µg Ab; 10 µg BP | $361.00 | |||
PP2A-Aα/β (B-1) Neutralizing Peptide | sc-374264 P | 100 µg/0.5 ml | $69.00 |