POPX2 Antibody (G-10): sc-393806

POPX2 Antibody (G-10) is a mouse monoclonal IgG1 antibody that detects POPX2 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POPX2, also known as partner of PIX 2, PPM1F, or CaMKPase, is a member of the PP2C family of serine/threonine phosphatases, which play a crucial role in regulating cellular stress response pathways. POPX2 is ubiquitously expressed, participating in various cellular processes, including the modulation of kinase activities. POPX2 interacts with CaMKII, a key regulator of calcium signaling and synaptic plasticity, thereby influencing neuronal function and survival. POPX2′s ability to regulate CaMKII activity is particularly important, as dysregulation of this interaction can lead to impaired neuronal signaling and contribute to neurodegenerative diseases. POPX2′s involvement in caspase-dependent apoptosis highlights its significance in cell death pathways, making POPX2 a critical player in maintaining cellular homeostasis. With versatile applications and essential role in cellular regulation, anti-POPX2 antibody (G-10) serves as an invaluable tool for researchers studying the intricate mechanisms of cell signaling and apoptosis.

The preferred POPX2 antibody is POPX2 Antibody (E-2): sc-514894.