Date published: 2025-12-18

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POPX2 Activators

POPX2 Activators refer to a collection of chemical compounds specifically tailored to augment the function or expression of the POPX2 protein. POPX2, which stands for Partner of PIX 2, is also known in some scientific circles as PPM1F. This protein is a serine/threonine protein phosphatase, playing a pivotal role in numerous cellular operations, most notably in modulating cell motility and migration. By dephosphorylating its target substrates, POPX2 maintains a balance in the cellular phosphorylation state, ensuring that cellular functions proceed seamlessly. Given the importance of phosphorylation in cellular signaling, compounds that can boost the activity of POPX2 offer a valuable tool for researchers delving into cell signaling and communication.

Chemicals categorized as POPX2 activators typically function through a myriad of mechanisms, each honing in on the primary objective of amplifying POPX2's activity or its cellular presence. Some of these activators could directly facilitate the protein's binding to its substrates, thereby enhancing its regulatory influence within cellular pathways. Others might act upstream, modulating the signaling pathways that govern the expression or activation of POPX2, ensuring a heightened presence or activity of the protein. Furthermore, some activators might interact directly with POPX2, modifying its structural configuration to foster a more active state conducive for its phosphatase function. A comprehensive grasp of POPX2 activators not only expands our understanding of cellular phosphorylation dynamics but also sheds light on the intricate web of cellular signaling that underpins many physiological processes.

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$76.00
$265.00
80
(4)

Another calcium ionophore that can potentially affect calcium-sensitive phosphatases.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$96.00
$334.00
50
(3)

Known to influence cell migration, it might have an indirect effect on POPX2.

D-erythro-Sphingosine-1-phosphate

26993-30-6sc-201383
sc-201383D
sc-201383A
sc-201383B
sc-201383C
1 mg
2 mg
5 mg
10 mg
25 mg
$162.00
$316.00
$559.00
$889.00
$1693.00
7
(1)

As a bioactive lipid, it might have effects on pathways associated with POPX2.

C2 Ceramide

3102-57-6sc-201375
sc-201375A
5 mg
25 mg
$77.00
$316.00
12
(1)

Another bioactive lipid known to influence various signaling pathways.