POPX2 Antibody (B-7): sc-514794

POPX2 Antibody (B-7) is a mouse monoclonal IgG1 antibody that detects POPX2 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). POPX2, also known as partner of PIX 2, PPM1F, or CaM-kinase phosphatase, is a member of the PP2C family of serine/threonine phosphatases, which play a crucial role in regulating various cellular functions, including cell stress responses. POPX2 is ubiquitously expressed, allowing participation in diverse cellular processes across different tissues. POPX2 interacts with CaMKII, a key regulator of calcium signaling pathways, and can influence neuronal function and plasticity. POPX2 regulation of CaMKII is particularly important because POPX2 can modulate synaptic strength and contribute to learning and memory processes. Furthermore, overexpression of POPX2 has been linked to caspase-dependent apoptosis, highlighting POPX2′s role in programmed cell death and cellular homeostasis. POPX2′s ability to negatively regulate the activity of αPAK, a protein kinase involved in actin dynamics, underscores POPX2′s significance in maintaining cellular architecture and function. With versatile applications and critical role in cellular signaling, anti-POPX2 antibody (B-7) is an essential tool for researchers studying the intricate mechanisms of cell regulation and signaling pathways.

The preferred POPX2 antibody is POPX2 Antibody (E-2): sc-514894.