
POLR2G Antibody (2781C2a) is a mouse monoclonal IgG1 antibody that detects POLR2G in mouse, rat, and human samples through western blotting (WB) and immunoprecipitation (IP) applications. POLR2G, also known as RPB7, hRPB19, or hsRPB7, is a crucial component of RNA polymerase II, a multi-subunit enzyme essential for the transcription of protein-coding genes. POLR2G plays a vital role in transcription initiation by forming a subcomplex with the RPB4 subunit, which is integral to RNA polymerase II complex function. POLR2G and RPB4 interaction helps maintain polymerase structural integrity and prevents double-stranded DNA from entering the active site in its closed conformation, ensuring accurate transcription initiation. POLR2G coordination with other subunits and transcription factors highlights its importance in regulating gene expression, making POLR2G a key target for studies related to transcriptional control and its implications in various biological processes and diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
POLR2G Antibody (2781C2a) | sc-81112 | 100 µg/ml | $339.00 |