podoplanin Antibody (F-3): sc-376962

Podoplanin Antibody (F-3) is a mouse monoclonal IgG2b kappa light chain antibody designed to detect podoplanin, also known as glycoprotein 38 (gp38), T1-alpha, Aggrus, or PA2.26 antigen, across mouse, rat, and human species using western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA) techniques. Anti-podoplanin antibody (F-3) targets amino acids 1-162 of the full-length human podoplanin protein, ensuring exceptional affinity and specificity. Podoplanin is a type I transmembrane glycoprotein that plays a critical role in various cellular processes, including cell adhesion, migration, and signaling. Podoplanin interacts with several key proteins such as CLEC-2, which is essential for platelet aggregation, and the ERM (Ezrin-Radixin-Moesin) family of proteins, which link the actin cytoskeleton to the plasma membrane, thereby influencing cell shape and motility. Additionally, podoplanin interacts with CD44 and Filamin A, facilitating important pathways in lymphangiogenesis and immune cell trafficking. Located primarily in stromal cells of peripheral lymphoid tissues and thymic epithelial cells, podoplanin is integral to maintaining the structural integrity and unique morphology of podocytes in the kidneys. Podoplanin monoclonal antibody (F-3) enables detailed studies of interactions and functions in immune responses, lymphatic development, and renal physiology. Anti-podoplanin antibody (F-3) is available in both non-conjugated form and a variety of conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® variants, providing versatility for diverse experimental applications. Podoplanin monoclonal antibody (F-3) is an invaluable tool for researchers investigating the multifaceted roles of podoplanin in cellular structure and function within the immune and renal systems.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-podoplanin Antibody (F-3) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-podoplanin Antibody (F-3) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

podoplanin Antibody (F-3) Specifications

Alternate Product Name: podoplanin

Product Clone Name: F-3

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 1-162

Epitope Target: podoplanin

Epitope Species: human

Product Reactivity/Detection: podoplanin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for podoplanin Antibody (F-3): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred podoplanin antibody is podoplanin Antibody (8.1.1): sc-53533.