Anti-PGC-1β Antibody (E-9) is a mouse monoclonal IgG2a (kappa light chain) PGC-1β antibody provided at 200 µg/ml
raised against amino acids 452-593 mapping within an internal region of PGC-1β of mouse origin
Anti-PGC-1 beta Antibody (E-9) is recommended for detection of PGC-1β of mouse and rat origin by WB, IP, IF and ELISA
Anti-PGC-1 beta Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
TransCruz reagent for Gel Supershift and ChIP applications (sc-373771 X, 200 µg/0.1 ml)
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of PGC-1β (E-9): sc-373771.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
PGC-1β Antibody (E-9) is a high quality monoclonal PGC-1 beta antibody (also designated PGC-1β antibody) suitable for the detection of the PGC-1 beta protein of mouse and rat origin. PGC-1β Antibody (E-9) is available as both the non-conjugated anti-PGC-1 beta antibody form, as well as multiple conjugated forms of anti-PGC-1 beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Transcription factors exert their effects by associating with coactivator or corepressor proteins. The coactivator complexes are thought to be constitutively active, requiring only proper positioning in the genome to initiate transcription. Coactivators include the steroid receptor coactivator (SRC) and CREB binding protein (CBP) families that contain histone acetyltransferase (HAT) activity, which modifies chromatin structure. PPAR gamma coactivator-1β (PGC-1β), also known as PERC or PPARGC1B, functions as a transcriptional activator for NRF-1 (nuclear respiratory factor-1), ERα (estrogen receptor alpha) and GR (glucocorticoid receptor). Through its interaction with various receptors, PGC-1β is involved in the regulation of mitochondrial biogenesis events such as energy expenditure and non-oxidative glucose metabolism. Expressed throughout the body with the highest expression in brain, heart and skeletal muscle, PGC-1β is induced by insulin and repressed by saturated fatty acids. The gene encoding PGC-1β is polymorphic and variations in the expressed protein may contribute to the development of obesity.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences