Peripherin Antibody (C6): sc-53992
- Peripherin Antibody (C6) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- raised against Peripherin of bovine origin
- recommended for detection of Peripherin of bovine origin by WB and IF
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Peripherin Antibody (C6) for WB applications. These reagents are now offered in bundles with Peripherin Antibody (C6) (see ordering information below).
QUICK LINKS
SEE ALSO...
Peripherin Antibody (C6) is a mouse monoclonal IgG1 antibody that detects Peripherin in bovine samples through applications such as western blotting (WB) and immunofluorescence (IF). Peripherin is a type III intermediate filament protein that plays a crucial role in the structural integrity and function of neurons, particularly in the peripheral nervous system and certain regions of the central nervous system. Anti-Peripherin antibody (C6) is essential for studying the formation of the cellular intermediate filament network, which provides mechanical support and stability to the cell, thereby facilitating proper neuronal function and resilience against stress. Notably, Peripherin is unique among intermediate filament proteins due to its susceptibility to post-translational modifications, specifically tyrosine phosphorylation. This modification can influence Peripherin′s interactions and stability, potentially impacting neuronal health and response to injury. Peripherin (C6) monoclonal antibody is an invaluable tool for researchers studying neuronal dynamics and the underlying mechanisms of neurodegenerative diseases, as anti-Peripherin antibody (C6) allows for the visualization and analysis of Peripherin expression and localization in various experimental contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Peripherin Antibody (C6) References:
- Cyclic GMP-gated channel and peripherin/rds-rom-1 complex of rod cells. | Molday, RS., et al. 1999. Novartis Found Symp. 224: 249-61; discussion 261-4. PMID: 10614055
- Role of peripherin/rds in vertebrate photoreceptor architecture and inherited retinal degenerations. | Goldberg, AF. 2006. Int Rev Cytol. 253: 131-75. PMID: 17098056
- The type III neurofilament peripherin is expressed in the tuberomammillary neurons of the mouse. | Eriksson, KS., et al. 2008. BMC Neurosci. 9: 26. PMID: 18294400
- The spectrum of retinal dystrophies caused by mutations in the peripherin/RDS gene. | Boon, CJ., et al. 2008. Prog Retin Eye Res. 27: 213-35. PMID: 18328765
- Expression of peripherin in human cochlea. | Liu, W., et al. 2010. Cell Tissue Res. 342: 345-51. PMID: 21088854
- α-Internexin and Peripherin: Expression, Assembly, Functions, and Roles in Disease. | Zhao, J. and Liem, RK. 2016. Methods Enzymol. 568: 477-507. PMID: 26795481
- Enterovirus-A71 exploits peripherin and Rac1 to invade the central nervous system. | Lim, ZQ., et al. 2021. EMBO Rep. 22: e51777. PMID: 33871166
- Developmental Changes in Peripherin-eGFP Expression in Spiral Ganglion Neurons. | Elliott, KL., et al. 2021. Front Cell Neurosci. 15: 678113. PMID: 34211371
- Evaluation of peripherin in biofluids of patients with motor neuron diseases. | Sabbatini, D., et al. 2021. Ann Clin Transl Neurol. 8: 1750-1754. PMID: 34264016
- Cryo-EM structures of peripherin-2 and ROM1 suggest multiple roles in photoreceptor membrane morphogenesis. | El Mazouni, D. and Gros, P. 2022. Sci Adv. 8: eadd3677. PMID: 36351012
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Peripherin Antibody (C6) | sc-53992 | 200 µg/ml | $322.00 | |||
Peripherin Antibody (C6): m-IgG Fc BP-HRP Bundle | sc-537030 | 200 µg Ab; 10 µg BP | $361.00 | |||
Peripherin Antibody (C6): m-IgGκ BP-HRP Bundle | sc-534213 | 200 µg Ab; 40 µg BP | $361.00 | |||
Peripherin Antibody (C6): m-IgG1 BP-HRP Bundle | sc-544968 | 200 µg Ab; 20 µg BP | $361.00 |