Peripherin Inhibitors
Peripherin inhibitors are a class of chemical compounds that have garnered significant attention in the field of molecular biology and neuroscience due to their unique mechanism of action and implications in understanding various cellular processes. These inhibitors specifically target peripherin, a type III intermediate filament protein found primarily in the peripheral nervous system, particularly in neurons and sensory ganglia. Peripherin is a cytoskeletal protein that plays a crucial role in maintaining the structural integrity and function of neurons, making it an intriguing target for research.
Peripherin inhibitors work by interfering with the normal functioning of peripherin, often by binding to specific regions of the protein or modulating its expression. By doing so, they can disrupt the formation of peripherin filaments, which are essential for maintaining the structural stability of neurons. This disruption can lead to altered cellular architecture and impacts various cellular processes. Researchers have been studying peripherin inhibitors to better understand their effects on neuronal function and to explore their relevance in various neurological conditions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
This DNA methyltransferase inhibitor may reduce peripherin expression by inducing hypomethylation, altering transcription regulation. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, it can change chromatin structure, potentially downregulating peripherin expression through epigenetic modifications. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid influences gene expression via its nuclear receptors, which could lead to altered transcriptional activity affecting peripherin expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Known for its role in activating sirtuins and modulating various signaling pathways, resveratrol could potentially impact peripherin expression indirectly. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin is known to modulate numerous molecular targets and could influence peripherin expression through its effects on signaling pathways and transcription factors. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
This isoflavone has been shown to have epigenetic effects, potentially modifying the expression of genes like peripherin through histone acetylation and DNA methylation changes. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can influence various signaling pathways and transcription factors, which might lead to changes in peripherin expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Acting as a histone deacetylase inhibitor, sodium butyrate could alter chromatin structure, potentially reducing peripherin expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
As a histone deacetylase inhibitor, Suberoylanilide Hydroxamic Acid can alter chromatin structure and potentially modulate peripherin expression. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $37.00 $152.00 | 11 | |
While primarily known for its role in inhibiting thymidylate synthase,Fluorouracil might also influence gene expression, potentially impacting peripherin. | ||||||